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OR6A2 olfactory receptor family 6 subfamily A member 2 [ Homo sapiens (human) ]

Gene ID: 8590, updated on 24-Nov-2020

Summary

Official Symbol
OR6A2provided by HGNC
Official Full Name
olfactory receptor family 6 subfamily A member 2provided by HGNC
Primary source
HGNC:HGNC:15301
See related
Ensembl:ENSG00000184933 MIM:608495
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
I7; OR6A1; OR6A2P; OR11-55
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See OR6A2 in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (6791736..6799689, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6815756..6817139, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily AG member 2 Neighboring gene olfactory receptor family 2 subfamily AG member 1 Neighboring gene phosphorylated adaptor for RNA export pseudogene Neighboring gene olfactory receptor family 10 subfamily A member 5

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC126538, MGC126540

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
olfactory receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
sensory perception of smell NAS
Non-traceable Author Statement
more info
PubMed 
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane NAS
Non-traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 6A2
Names
hI7 olfactory receptor
hP2 olfactory receptor
olfactory receptor 11-55
olfactory receptor 6A1
olfactory receptor OR11-83
olfactory receptor, family 6, subfamily A, member 1
olfactory receptor, family 6, subfamily A, member 2 pseudogene
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_003696.3NP_003687.2  olfactory receptor 6A2

    See identical proteins and their annotated locations for NP_003687.2

    Status: VALIDATED

    Source sequence(s)
    AC087280
    Consensus CDS
    CCDS7772.1
    UniProtKB/Swiss-Prot
    O95222
    UniProtKB/TrEMBL
    A0A126GW91
    Related
    ENSP00000492990.1, ENST00000641196.1
    Conserved Domains (1) summary
    cd15224
    Location:41299
    7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    6791736..6799689 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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