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MDM36 Mdm36p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856198, updated on 18-Sep-2024

Summary

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Official Symbol
MDM36
Official Full Name
Mdm36p
Primary source
SGD:S000006287
Locus tag
YPR083W
See related
AllianceGenome:SGD:S000006287; FungiDB:YPR083W; VEuPathDB:YPR083W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitochondrial fission and mitochondrion inheritance. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (704854..706593)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene putative glycine--tRNA ligase Neighboring gene U4/U6-U5 snRNP complex subunit DIB1 Neighboring gene uncharacterized protein Neighboring gene Asa1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biochemical Characterization of the Num1-Mdm36 Complex at the Mitochondria-Plasma Membrane Contact Site. Won J, et al. Mol Cells, 2021 Apr 30. PMID 33827993, Free PMC Article
  2. Num1 anchors mitochondria to the plasma membrane via two domains with different lipid binding specificities. Ping HA, et al. J Cell Biol, 2016 Jun 6. PMID 27241910, Free PMC Article
  3. Overexpression of Mdm36 reveals Num1 foci that mediate dynein-dependent microtubule sliding in budding yeast. Omer S, et al. J Cell Sci, 2020 Oct 15. PMID 32938686, Free PMC Article
  4. The yeast cell cortical protein Num1 integrates mitochondrial dynamics into cellular architecture. Klecker T, et al. J Cell Sci, 2013 Jul 1. PMID 23641071
  5. Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria. Lackner LL, et al. Proc Natl Acad Sci U S A, 2013 Feb 5. PMID 23341591, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Biochemical Characterization of the Num1-Mdm36 Complex at the Mitochondria-Plasma Membrane Contact Site.
    Title: Biochemical Characterization of the Num1-Mdm36 Complex at the Mitochondria-Plasma Membrane Contact Site.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular distribution of mitochondria IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrial fission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrion inheritance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Mdm36p
NP_015408.1
  • Mitochondrial protein; required for normal mitochondrial morphology and inheritance; component of the mitochondria-ER-cortex-anchor (MECA); interacts with Num1p to link the ER and mitochondria at the cell cortex; proposed involvement in the formation of Dnm1p and Num1p-containing cortical anchor complexes that promote mitochondrial fission

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    704854..706593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184180.1 → NP_015408.1  TPA: Mdm36p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015408.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W485, Q06820
    UniProtKB/TrEMBL
    A6ZWW8, B3LK53, C7GPS6, C8ZJA8, N1NVK6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06820.1

Gene LinkOut

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