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IES2 Ies2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855506, updated on 17-May-2024

Summary

Gene symbol
IES2
Gene description
Ies2p
Primary source
FungiDB:YNL215W
Locus tag
YNL215W
See related
SGD:S000005159; AllianceGenome:SGD:S000005159; VEuPathDB:YNL215W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable DNA binding activity. Predicted to be involved in DNA repair and chromatin remodeling. Located in nucleus. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See IES2 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (244468..245430)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene putative serine/threonine-protein phosphatase Neighboring gene DNA-binding transcription factor RAP1 Neighboring gene Pex17p Neighboring gene Rrg9p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Ino80 complex IEA
Inferred from Electronic Annotation
more info
 
part_of Ino80 complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ies2p
NP_014184.1
  • Protein that associates with the INO80 chromatin remodeling complex; associates with the INO80 complex under low-salt conditions; essential for growth under anaerobic conditions; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    244468..245430
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183053.1NP_014184.1  TPA: Ies2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014184.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0X5, P40154
    UniProtKB/TrEMBL
    A0A6A5Q5B4, A6ZRM5, B3LP59, B5VQJ7, C7GPE2, G2WLP8, N1NZ65
    Conserved Domains (1) summary
    pfam04795
    Location:237297
    PAPA-1; PAPA-1-like conserved region