Format

Send to:

Choose Destination

CNTNAP4 contactin associated protein family member 4 [ Homo sapiens (human) ]

Gene ID: 85445, updated on 9-Aug-2021

Summary

Official Symbol
CNTNAP4provided by HGNC
Official Full Name
contactin associated protein family member 4provided by HGNC
Primary source
HGNC:HGNC:18747
See related
Ensembl:ENSG00000152910 MIM:610518
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CASPR4
Summary
This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016]
Expression
Biased expression in brain (RPKM 7.4) and adrenal (RPKM 0.3) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See CNTNAP4 in Genome Data Viewer
Location:
16q23.1
Exon count:
29
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (76277376..76563610)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (76311299..76594654)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371349 Neighboring gene ribosomal protein L18 pseudogene 13 Neighboring gene RN7SK pseudogene 233 Neighboring gene long intergenic non-protein coding RNA 2125 Neighboring gene uncharacterized LOC105376774

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
GeneReviews: Not available
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
GeneReviews: Not available
Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.
GeneReviews: Not available
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1763

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of grooming behavior ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of synaptic transmission, GABAergic ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of synaptic transmission, dopaminergic ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in presynaptic membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
contactin-associated protein-like 4
Names
cell recognition molecule Caspr4
contactin associated protein like 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322178.2NP_001309107.1  contactin-associated protein-like 4 isoform 3 precursor

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (9) summary
    smart00231
    Location:55177
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:912946
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:744888
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:503534
    EGF; EGF-like domain
    pfam02210
    Location:212341
    Laminin_G_2; Laminin G domain
    cl00085
    Location:542589
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:554637
    COLFI; Fibrillar collagen C-terminal domain
    cl22861
    Location:371429
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
  2. NM_001322179.2NP_001309108.1  contactin-associated protein-like 4 isoform 4 precursor

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (7) summary
    smart00231
    Location:55177
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:371521
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:553584
    EGF; EGF-like domain
    pfam02210
    Location:212341
    Laminin_G_2; Laminin G domain
    cl00085
    Location:592639
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:604687
    COLFI; Fibrillar collagen C-terminal domain
  3. NM_001322180.2NP_001309109.1  contactin-associated protein-like 4 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (8) summary
    smart00231
    Location:348
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:833867
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:347
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:665809
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:424455
    EGF; EGF-like domain
    pfam02210
    Location:83212
    Laminin_G_2; Laminin G domain
    cl00085
    Location:463510
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:475558
    COLFI; Fibrillar collagen C-terminal domain
  4. NM_001322181.2NP_001309110.1  contactin-associated protein-like 4 isoform 6 precursor

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (8) summary
    smart00231
    Location:55176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:961995
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:54175
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:793937
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:552583
    EGF; EGF-like domain
    pfam02210
    Location:211340
    Laminin_G_2; Laminin G domain
    cl00085
    Location:591638
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:603686
    COLFI; Fibrillar collagen C-terminal domain
  5. NM_001322187.2NP_001309116.1  contactin-associated protein-like 4 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (7) summary
    cd00054
    Location:490524
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:322466
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:81112
    EGF; EGF-like domain
    pfam02210
    Location:574704
    Laminin_G_2; Laminin G domain
    cl00085
    Location:120167
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:132215
    COLFI; Fibrillar collagen C-terminal domain
    cl22861
    Location:252
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
  6. NM_001322188.2NP_001309117.1  contactin-associated protein-like 4 isoform 8 precursor

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (8) summary
    smart00231
    Location:55177
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:962996
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:794938
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:553584
    EGF; EGF-like domain
    pfam02210
    Location:212341
    Laminin_G_2; Laminin G domain
    cl00085
    Location:592639
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:604687
    COLFI; Fibrillar collagen C-terminal domain
  7. NM_001322189.2NP_001309118.1  contactin-associated protein-like 4 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (8) summary
    smart00231
    Location:389
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:874908
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:188
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:706850
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:465496
    EGF; EGF-like domain
    pfam02210
    Location:124253
    Laminin_G_2; Laminin G domain
    cl00085
    Location:504551
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:516599
    COLFI; Fibrillar collagen C-terminal domain
  8. NM_001322190.2NP_001309119.1  contactin-associated protein-like 4 isoform 10 precursor

    Status: REVIEWED

    Source sequence(s)
    AB100092, AC106741, AC108125, FO681478
    Consensus CDS
    CCDS82015.1
    UniProtKB/TrEMBL
    A0A087WTA1, Q86YZ8
    Related
    ENSP00000477698.1, ENST00000622250.4
    Conserved Domains (8) summary
    smart00231
    Location:55177
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:914948
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:746890
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:505536
    EGF; EGF-like domain
    pfam02210
    Location:9981128
    Laminin_G_2; Laminin G domain
    cl00085
    Location:544591
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:556639
    COLFI; Fibrillar collagen C-terminal domain
  9. NM_001322191.2NP_001309120.1  contactin-associated protein-like 4 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
    Conserved Domains (7) summary
    cd00054
    Location:653687
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:485629
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:244275
    EGF; EGF-like domain
    pfam02210
    Location:737867
    Laminin_G_2; Laminin G domain
    cl00085
    Location:283330
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:295378
    COLFI; Fibrillar collagen C-terminal domain
    cl22861
    Location:132
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
  10. NM_033401.5NP_207837.2  contactin-associated protein-like 4 isoform 1 precursor

    See identical proteins and their annotated locations for NP_207837.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AB051550, AC106741, AC108125, BM544789, Z44514
    Consensus CDS
    CCDS73915.1
    UniProtKB/Swiss-Prot
    Q9C0A0
    Related
    ENSP00000479811.1, ENST00000611870.5
    Conserved Domains (8) summary
    smart00231
    Location:55177
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:962996
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:794938
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:553584
    EGF; EGF-like domain
    pfam02210
    Location:212341
    Laminin_G_2; Laminin G domain
    cl00085
    Location:592639
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:604687
    COLFI; Fibrillar collagen C-terminal domain
  11. NM_138994.5NP_620481.2  contactin-associated protein-like 4 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR and CDS and lacks several coding exons, compared to variant 1. It encodes a shorter protein (isoform 2) which has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AB100093, AC106741, AC108125, DA319383, DB050637, DT217898
    Consensus CDS
    CCDS10924.2
    UniProtKB/Swiss-Prot
    Q9C0A0
    Related
    ENSP00000418741.1, ENST00000478060.5
    Conserved Domains (8) summary
    smart00231
    Location:30152
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:889923
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:29151
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:721865
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:480511
    EGF; EGF-like domain
    pfam02210
    Location:9731103
    Laminin_G_2; Laminin G domain
    cl00085
    Location:519566
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:531614
    COLFI; Fibrillar collagen C-terminal domain

RNA

  1. NR_136210.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
  2. NR_136213.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478
  3. NR_136216.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC010528, AC106741, AC108125, FO681478

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    76277376..76563610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023805.2XP_016879294.1  contactin-associated protein-like 4 isoform X2

    Conserved Domains (7) summary
    cd00054
    Location:653687
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00110
    Location:485629
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:244275
    EGF; EGF-like domain
    pfam02210
    Location:737867
    Laminin_G_2; Laminin G domain
    cl00085
    Location:283330
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:295378
    COLFI; Fibrillar collagen C-terminal domain
    cl22861
    Location:132
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
  2. XM_011523403.2XP_011521705.1  contactin-associated protein-like 4 isoform X1

    Conserved Domains (8) summary
    smart00231
    Location:30152
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00054
    Location:937971
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00057
    Location:29151
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:769913
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:528559
    EGF; EGF-like domain
    pfam02210
    Location:187316
    Laminin_G_2; Laminin G domain
    cl00085
    Location:567614
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    cl02436
    Location:579662
    COLFI; Fibrillar collagen C-terminal domain

RNA

  1. XR_001752013.1 RNA Sequence

Support Center