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VMA21 Vma21p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852997, updated on 9-Jun-2024

Summary

Gene symbol
VMA21
Gene description
Vma21p
Primary source
FungiDB:YGR105W
Locus tag
YGR105W
See related
SGD:S000003337; AllianceGenome:SGD:S000003337; VEuPathDB:YGR105W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in vacuolar proton-transporting V-type ATPase complex assembly. Located in endoplasmic reticulum membrane. Used to study X-linked myopathy with excessive autophagy. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See VMA21 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (698599..698832)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene mRNA-binding ribosome synthesis protein NOP7 Neighboring gene Srb5p Neighboring gene Voa1p Neighboring gene tRNA-Leu

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Vma21p
NP_011619.3
  • Integral membrane protein required for V-ATPase function; not actual component of vacuolar H+-ATPase (V-ATPase) complex; diverged ortholog of human VMA21/XMEA (X-linked Myopathy with Excessive Autophagy); functions in assembly of V-ATPase; localizes to endoplasmic reticulum (ER)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    698599..698832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181234.3NP_011619.3  TPA: Vma21p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011619.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZV87, B3LIC1, D6VUN7, P41806, Q6Q5Q3
    UniProtKB/TrEMBL
    A0A6A5PYN5, C7GWV8, C8Z8Z8, G2WEJ0, N1P9W3
    Conserved Domains (1) summary
    pfam09446
    Location:961
    VMA21; VMA21-like domain