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FIT1 Fit1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852147, updated on 18-Sep-2024

Summary

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Official Symbol
FIT1
Official Full Name
Fit1p
Primary source
SGD:S000002942
Locus tag
YDR534C
See related
AllianceGenome:SGD:S000002942; FungiDB:YDR534C; VEuPathDB:YDR534C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ATP binding activity. Involved in siderophore transport. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See FIT1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1503314..1504900, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Kre28p Neighboring gene glutathione-independent methylglyoxalase Neighboring gene glucose-inactivated glycerol proton symporter STL1 Neighboring gene phenylacrylic acid decarboxylase PAD1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The localization change of Ybr078w/Ecm33, a yeast GPI-associated protein, from the plasma membrane to the cell wall, affecting the cellular function. Terashima H, et al. FEMS Microbiol Lett, 2003 Jan 21. PMID 12583915
  2. Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae. Protchenko O, et al. J Biol Chem, 2001 Dec 28. PMID 11673473
  3. Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. Foury F, et al. J Biol Chem, 2001 Mar 16. PMID 11112771
  4. The response to iron deprivation in Saccharomyces cerevisiae: expression of siderophore-based systems of iron uptake. Philpott CC, et al. Biochem Soc Trans, 2002 Aug. PMID 12196168
  5. Laboratory evolution of new lactate transporter genes in a jen1Δ mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis. de Kok S, et al. FEMS Yeast Res, 2012 May. PMID 22257278

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fit1p
NP_010823.1
  • Mannoprotein that is incorporated into the cell wall; incorporated via a glycosylphosphatidylinositol (GPI) anchor; involved in the retention of siderophore-iron in the cell wall

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1503314..1504900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180842.1 → NP_010823.1  TPA: Fit1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010823.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTF5, Q04433
    UniProtKB/TrEMBL
    G2WBR1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04433.1

Gene LinkOut

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