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SED5 t-SNARE syntaxin [ Saccharomyces cerevisiae S288C ]

Gene ID: 850713, updated on 18-Jan-2023

Summary

Gene symbol
SED5
Gene description
t-SNARE syntaxin
Primary source
SGD:S000004016
Locus tag
YLR026C
See related
AllianceGenome:SGD:S000004016
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables SNAP receptor activity. Involved in Golgi vesicle transport and regulation of inclusion body assembly. Located in cis-Golgi network. Is integral component of membrane. Part of SNARE complex. Orthologous to human STX5 (syntaxin 5). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See SED5 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (195450..196472, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene putative ubiquitin-protein ligase UBR2 Neighboring gene ESCRT-III subunit protein SNF7 Neighboring gene aspartate transaminase AAT2 Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SED5 gene: The SED5 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables SNAP receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intra-Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of inclusion body assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in vesicle docking IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vesicle fusion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in vesicle fusion IEA
Inferred from Electronic Annotation
more info
 
involved_in vesicle fusion with Golgi apparatus IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of SNARE complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cis-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in organelle membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
t-SNARE syntaxin
NP_013126.1
  • cis-Golgi t-SNARE syntaxin; required for vesicular transport between the ER and the Golgi complex; binds at least 9 SNARE proteins; plays a role in autophagy by regulating formation of autophagic vesicles in Golgi

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    195450..196472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181913.1NP_013126.1  TPA: t-SNARE syntaxin [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013126.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY28, Q01590
    UniProtKB/TrEMBL
    A0A0L8VLB6, A0A6A5PR90, A7A0T2, B5VMW4, C7GXH2, C8ZCZ8, N1P027
    Conserved Domains (1) summary
    cd15844
    Location:252324
    SNARE_syntaxin5; SNARE motif of syntaxin 5