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C1orf198 chromosome 1 open reading frame 198 [ Homo sapiens (human) ]

Gene ID: 84886, updated on 12-Aug-2022

Summary

Official Symbol
C1orf198provided by HGNC
Official Full Name
chromosome 1 open reading frame 198provided by HGNC
Primary source
HGNC:HGNC:25900
See related
Ensembl:ENSG00000119280 AllianceGenome:HGNC:25900
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung (RPKM 42.9), brain (RPKM 27.3) and 24 other tissues See more
Orthologs
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Genomic context

See C1orf198 in Genome Data Viewer
Location:
1q42.2
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (230837119..230869591, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (230217591..230250052, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (230972865..231005337, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 79 Neighboring gene uncharacterized LOC124904548 Neighboring gene VISTA enhancer hs1766 Neighboring gene uncharacterized LOC101927604 Neighboring gene uncharacterized LOC124904547 Neighboring gene uncharacterized LOC105373167 Neighboring gene RNA, 7SL, cytoplasmic 837, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14525, FLJ16283, FLJ38847, MGC10710, DKFZp667D152

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
uncharacterized protein C1orf198

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136494.2NP_001129966.1  uncharacterized protein C1orf198 isoform 2

    See identical proteins and their annotated locations for NP_001129966.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK096166, AL118511, BC066649
    Consensus CDS
    CCDS44330.1
    UniProtKB/Swiss-Prot
    Q9H425
    Related
    ENSP00000428172.1, ENST00000470540.5
    Conserved Domains (1) summary
    pfam15797
    Location:193
    DUF4706; Domain of unknown function (DUF4706)
  2. NM_001136495.2NP_001129967.1  uncharacterized protein C1orf198 isoform 3

    See identical proteins and their annotated locations for NP_001129967.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AK292433, BC066649, DA333501
    Consensus CDS
    CCDS44331.1
    UniProtKB/Swiss-Prot
    Q9H425
    Related
    ENSP00000430967.1, ENST00000523410.1
  3. NM_032800.3NP_116189.1  uncharacterized protein C1orf198 isoform 1

    See identical proteins and their annotated locations for NP_116189.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AL118511
    Consensus CDS
    CCDS1587.1
    UniProtKB/Swiss-Prot
    G5EA08, Q9H425
    UniProtKB/TrEMBL
    A0A024R3S1, A1NYL2
    Related
    ENSP00000355623.5, ENST00000366663.10
    Conserved Domains (1) summary
    pfam15797
    Location:31131
    DUF4706; Domain of unknown function (DUF4706)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    230837119..230869591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047432496.1XP_047288452.1  uncharacterized protein C1orf198 isoform X2

  2. XM_047432495.1XP_047288451.1  uncharacterized protein C1orf198 isoform X1

  3. XM_017002599.3XP_016858088.1  uncharacterized protein C1orf198 isoform X4

    UniProtKB/Swiss-Prot
    Q9H425
  4. XM_047432504.1XP_047288460.1  uncharacterized protein C1orf198 isoform X4

  5. XM_047432497.1XP_047288453.1  uncharacterized protein C1orf198 isoform X3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    230217591..230250052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)