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MFSD9 major facilitator superfamily domain containing 9 [ Homo sapiens (human) ]

Gene ID: 84804, updated on 1-Aug-2020

Summary

Official Symbol
MFSD9provided by HGNC
Official Full Name
major facilitator superfamily domain containing 9provided by HGNC
Primary source
HGNC:HGNC:28158
See related
Ensembl:ENSG00000135953
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in duodenum (RPKM 4.6), colon (RPKM 4.2) and 25 other tissues See more
Orthologs

Genomic context

See MFSD9 in Genome Data Viewer
Location:
2q12.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (102713867..102736888, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (103331089..103353341, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 9 member A4 Neighboring gene solute carrier family 9 member A2 Neighboring gene transmembrane protein 182 Neighboring gene long intergenic non-protein coding RNA 1796

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
NHGRI GWA Catalog
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11332

Gene Ontology Provided by GOA

Function Evidence Code Pubs
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
major facilitator superfamily domain-containing protein 9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322080.1NP_001309009.1  major facilitator superfamily domain-containing protein 9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC007239, AK296768, BC009310, CA426861, U79290
    UniProtKB/Swiss-Prot
    Q8NBP5
    UniProtKB/TrEMBL
    B4DKY6
    Conserved Domains (2) summary
    cd06174
    Location:1395
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:1366
    MFS_1; Major Facilitator Superfamily
  2. NM_001322081.1NP_001309010.1  major facilitator superfamily domain-containing protein 9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC007239, AC007251, AK296768, BC006242, BC009310, CA426861, U79290
    UniProtKB/Swiss-Prot
    Q8NBP5
    UniProtKB/TrEMBL
    B4DKY6
    Conserved Domains (2) summary
    cd06174
    Location:1395
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:1366
    MFS_1; Major Facilitator Superfamily
  3. NM_032718.5NP_116107.3  major facilitator superfamily domain-containing protein 9 isoform 1

    See identical proteins and their annotated locations for NP_116107.3

    Status: VALIDATED

    Source sequence(s)
    AC007239, AK296768, BC006242, BC009310, U79290
    Consensus CDS
    CCDS2063.1
    UniProtKB/Swiss-Prot
    Q8NBP5
    UniProtKB/TrEMBL
    B4DKY6
    Related
    ENSP00000258436.5, ENST00000258436.10
    Conserved Domains (1) summary
    pfam07690
    Location:49427
    MFS_1; Major Facilitator Superfamily

RNA

  1. NR_136173.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007239, AK296768, AK307178, CA426861, U79290
  2. NR_136174.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007239, AK296768, AK307178, BC009310

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    102713867..102736888 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011512005.2XP_011510307.1  major facilitator superfamily domain-containing protein 9 isoform X1

    See identical proteins and their annotated locations for XP_011510307.1

    UniProtKB/TrEMBL
    B4DKY6
    Conserved Domains (2) summary
    cd06174
    Location:1395
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:1366
    MFS_1; Major Facilitator Superfamily
  2. XM_011512006.2XP_011510308.1  major facilitator superfamily domain-containing protein 9 isoform X2

    Conserved Domains (2) summary
    cd06174
    Location:29331
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:29302
    MFS_1; Major Facilitator Superfamily
  3. XM_011512007.2XP_011510309.1  major facilitator superfamily domain-containing protein 9 isoform X3

    Conserved Domains (2) summary
    cd06174
    Location:13315
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:13286
    MFS_1; Major Facilitator Superfamily

RNA

  1. XR_923047.2 RNA Sequence

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