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UNC119B unc-119 lipid binding chaperone B [ Homo sapiens (human) ]

Gene ID: 84747, updated on 21-Dec-2019

Summary

Official Symbol
UNC119Bprovided by HGNC
Official Full Name
unc-119 lipid binding chaperone Bprovided by HGNC
Primary source
HGNC:HGNC:16488
See related
Ensembl:ENSG00000175970
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
POC7B
Expression
Ubiquitous expression in thyroid (RPKM 22.0), ovary (RPKM 19.5) and 24 other tissues See more
Orthologs

Genomic context

See UNC119B in Genome Data Viewer
Location:
12q24.31
Exon count:
5
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (120710458..120723640)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (121148238..121161443)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene calcium binding protein 1 Neighboring gene uncharacterized LOC105370029 Neighboring gene malectin Neighboring gene microRNA 4700 Neighboring gene acyl-CoA dehydrogenase short chain Neighboring gene signal peptide peptidase like 3 Neighboring gene ADP ribosylation factor 1 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
An atlas of genetic influences on human blood metabolites.
NHGRI GWA Catalog
Human metabolic individuality in biomedical and pharmaceutical research.
NHGRI GWA Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC5139

Gene Ontology Provided by GOA

Function Evidence Code Pubs
lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lipid binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
lipoprotein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lipoprotein transport IDA
Inferred from Direct Assay
more info
PubMed 
nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
ciliary transition zone IDA
Inferred from Direct Assay
more info
PubMed 
cilium TAS
Traceable Author Statement
more info
 
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
protein unc-119 homolog B
Names
POC7 centriolar protein homolog B
unc-119 homolog B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080533.3NP_001074002.1  protein unc-119 homolog B

    See identical proteins and their annotated locations for NP_001074002.1

    Status: VALIDATED

    Source sequence(s)
    AC069234, AL137327, BC070088, DA324219
    Consensus CDS
    CCDS31914.1
    UniProtKB/Swiss-Prot
    A6NIH7
    UniProtKB/TrEMBL
    Q69YW6
    Related
    ENSP00000344942.4, ENST00000344651.5
    Conserved Domains (1) summary
    pfam05351
    Location:88247
    GMP_PDE_delta; GMP-PDE, delta subunit

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    120710458..120723640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_032661.1: Suppressed sequence

    Description
    NM_032661.1: This RefSeq was permanently suppressed because it contains the wrong CDS.
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