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LYZL1 lysozyme like 1 [ Homo sapiens (human) ]

Gene ID: 84569, updated on 26-Oct-2022

Summary

Official Symbol
LYZL1provided by HGNC
Official Full Name
lysozyme like 1provided by HGNC
Primary source
HGNC:HGNC:30502
See related
Ensembl:ENSG00000120563 AllianceGenome:HGNC:30502
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYC2; LYZD1; KAAG648; PRO1278; bA534G20.1
Summary
Predicted to enable lysozyme activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 12.4) See more
Orthologs
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Genomic context

See LYZL1 in Genome Data Viewer
Location:
10p12.1-p11.23
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (29289070..29318328)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (29320734..29342906)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (29577999..29600161)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984171 Neighboring gene uncharacterized LOC105376472 Neighboring gene uncharacterized LOC124902400 Neighboring gene uncharacterized LOC107984217 Neighboring gene uncharacterized LOC105376473 Neighboring gene uncharacterized LOC105376474

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC33408

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables lysozyme activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lysozyme-like protein 1
Names
lysozyme D1
NP_115906.4
XP_005252684.1
XP_016872280.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032517.6NP_115906.4  lysozyme-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AI393331, AL158167, BC021730, BF057063, BG209290, BP369317
    Consensus CDS
    CCDS31174.2
    UniProtKB/Swiss-Prot
    Q8WW16
    Related
    ENSP00000498092.1, ENST00000649382.2
    Conserved Domains (1) summary
    cd00119
    Location:20143
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    29289070..29318328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005252627.4XP_005252684.1  lysozyme-like protein 1 isoform X1

    Related
    ENSP00000364650.3, ENST00000375500.8
    Conserved Domains (1) summary
    cd00119
    Location:66172
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
  2. XM_017016791.2XP_016872280.1  lysozyme-like protein 1 isoform X2

RNA

  1. XR_428650.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    29320734..29342906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)