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LYZL1 lysozyme like 1 [ Homo sapiens (human) ]

Gene ID: 84569, updated on 1-Aug-2020

Summary

Official Symbol
LYZL1provided by HGNC
Official Full Name
lysozyme like 1provided by HGNC
Primary source
HGNC:HGNC:30502
See related
Ensembl:ENSG00000120563
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYC2; LYZD1; KAAG648; PRO1278; bA534G20.1
Expression
Restricted expression toward testis (RPKM 12.4) See more
Orthologs

Genomic context

See LYZL1 in Genome Data Viewer
Location:
10p12.1-p11.23
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (29289051..29318328)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (29577980..29607158)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376471 Neighboring gene uncharacterized LOC105376472 Neighboring gene uncharacterized LOC107984217 Neighboring gene uncharacterized LOC105376473 Neighboring gene uncharacterized LOC105376474

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC33408

Gene Ontology Provided by GOA

Function Evidence Code Pubs
lysozyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
defense response to Gram-negative bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
lysozyme-like protein 1
Names
lysozyme D1
NP_115906.4
XP_005252684.1
XP_016872280.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032517.6NP_115906.4  lysozyme-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AI393331, AL158167, BC021730, BF057063, BG209290, BP369317
    Consensus CDS
    CCDS31174.1
    Related
    ENSP00000498092.1, ENST00000649382.2
    Conserved Domains (1) summary
    cd00119
    Location:20143
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    29289051..29318328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005252627.3XP_005252684.1  lysozyme-like protein 1 isoform X1

    Related
    ENSP00000364650.3, ENST00000375500.8
    Conserved Domains (1) summary
    cd00119
    Location:66172
    LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
  2. XM_017016791.1XP_016872280.1  lysozyme-like protein 1 isoform X2

RNA

  1. XR_428650.1 RNA Sequence

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