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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_042869.2 RefSeqGene
- Range
-
5002..53327
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001281520.2 → NP_001268449.1 DNA helicase MCM8 isoform 1
See identical proteins and their annotated locations for NP_001268449.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (1).
- Source sequence(s)
-
AJ439063, AL035461, BC101057
- Consensus CDS
-
CCDS13094.1
- UniProtKB/Swiss-Prot
- Q969I5, Q9UJA3
- Related
- ENSP00000368174.3, ENST00000378896.7
- Conserved Domains (1) summary
-
- COG1241
Location:139 → 837
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
-
NM_001281521.2 → NP_001268450.1 DNA helicase MCM8 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an in-frame exon and uses an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) is longer, compared to isoform 1.
- Source sequence(s)
-
AJ439063, AL035461, BC008830, BC101055
- Consensus CDS
-
CCDS63227.1
- UniProtKB/Swiss-Prot
-
Q9UJA3
- Related
- ENSP00000368164.2, ENST00000378886.6
- Conserved Domains (3) summary
-
- cd00009
Location:475 → 633
- AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
- COG1241
Location:139 → 877
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
- pfam14551
Location:98 → 223
- MCM_N; MCM N-terminal domain
-
NM_001281522.2 → NP_001268451.1 DNA helicase MCM8 isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (4) is shorter, compared to isoform 1.
- Source sequence(s)
-
AJ439063, AK297806, AL035461, BC008830
- Consensus CDS
-
CCDS63226.1
- UniProtKB/Swiss-Prot
-
Q9UJA3
- UniProtKB/TrEMBL
-
B4DN82
- Related
- ENSP00000368161.1, ENST00000378883.5
- Conserved Domains (2) summary
-
- COG1241
Location:139 → 790
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
- pfam14551
Location:98 → 223
- MCM_N; MCM N-terminal domain
-
NM_032485.6 → NP_115874.3 DNA helicase MCM8 isoform 1
See identical proteins and their annotated locations for NP_115874.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform (1). Both variants 1 and 3 encode the same isoform.
- Source sequence(s)
-
AJ439063, AK297806, AL035461, BC008830
- Consensus CDS
-
CCDS13094.1
- UniProtKB/Swiss-Prot
- Q969I5, Q9UJA3
- UniProtKB/TrEMBL
-
B4DN82
- Related
- ENSP00000478141.1, ENST00000610722.4
- Conserved Domains (1) summary
-
- COG1241
Location:139 → 837
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
-
NM_182802.3 → NP_877954.1 DNA helicase MCM8 isoform 2
See identical proteins and their annotated locations for NP_877954.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the internal coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
- Source sequence(s)
-
AJ439063, AK297806, AL035461, AY158211
- Consensus CDS
-
CCDS13095.1
- UniProtKB/Swiss-Prot
-
Q9UJA3
- UniProtKB/TrEMBL
-
B4DN82
- Related
- ENSP00000265187.4, ENST00000265187.4
- Conserved Domains (3) summary
-
- cd00009
Location:419 → 577
- AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
- COG1241
Location:139 → 821
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
- pfam14551
Location:98 → 223
- MCM_N; MCM N-terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000020.11 Reference GRCh38.p14 Primary Assembly
- Range
-
5950652..5998977
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047440552.1 → XP_047296508.1 DNA helicase MCM8 isoform X2
-
XM_017028105.2 → XP_016883594.1 DNA helicase MCM8 isoform X1
- UniProtKB/Swiss-Prot
-
Q9UJA3
- Conserved Domains (3) summary
-
- cd00009
Location:475 → 633
- AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
- COG1241
Location:139 → 877
- Mcm2; DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair]
- pfam14551
Location:98 → 223
- MCM_N; MCM N-terminal domain
-
XM_047440553.1 → XP_047296509.1 DNA helicase MCM8 isoform X3
-
XM_047440555.1 → XP_047296511.1 DNA helicase MCM8 isoform X5
-
XM_047440554.1 → XP_047296510.1 DNA helicase MCM8 isoform X4
Alternate T2T-CHM13v2.0
Genomic
-
NC_060944.1 Alternate T2T-CHM13v2.0
- Range
-
5990987..6039282
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)