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ECRG4 ECRG4 augurin precursor [ Homo sapiens (human) ]

Gene ID: 84417, updated on 7-Jun-2020

Summary

Official Symbol
ECRG4provided by HGNC
Official Full Name
ECRG4 augurin precursorprovided by HGNC
Primary source
HGNC:HGNC:24642
See related
Ensembl:ENSG00000119147 MIM:611752
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C2orf40
Expression
Broad expression in fat (RPKM 29.6), thyroid (RPKM 20.4) and 17 other tissues See more
Orthologs

Genomic context

See ECRG4 in Genome Data Viewer
Location:
2q12.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (106063290..106078155)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (106682113..106694611)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373530 Neighboring gene uncharacterized LOC105373531 Neighboring gene UDP-glucuronate decarboxylase 1 Neighboring gene uncharacterized LOC107985930 Neighboring gene Sharpr-MPRA regulatory region 936

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
G1 to G0 transition IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular senescence IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
augurin
Names
esophageal cancer related gene 4 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032411.3NP_115787.1  augurin precursor

    See identical proteins and their annotated locations for NP_115787.1

    Status: VALIDATED

    Source sequence(s)
    AF325503, BC021742
    Consensus CDS
    CCDS2072.1
    UniProtKB/Swiss-Prot
    Q9H1Z8
    Related
    ENSP00000238044.3, ENST00000238044.8
    Conserved Domains (1) summary
    pfam15187
    Location:32148
    Augurin; Oesophageal cancer-related gene 4

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    106063290..106078155
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006712799.3XP_006712862.1  augurin isoform X2

    See identical proteins and their annotated locations for XP_006712862.1

    UniProtKB/TrEMBL
    B8ZZE5
    Related
    ENSP00000386421.1, ENST00000409944.5
    Conserved Domains (1) summary
    pfam15187
    Location:1112
    Augurin; Oesophageal cancer-related gene 4
  2. XM_011511993.2XP_011510295.1  augurin isoform X2

    See identical proteins and their annotated locations for XP_011510295.1

    UniProtKB/TrEMBL
    B8ZZE5
    Conserved Domains (1) summary
    pfam15187
    Location:1112
    Augurin; Oesophageal cancer-related gene 4
  3. XM_017005106.1XP_016860595.1  augurin isoform X1

    Related
    ENSP00000388664.1, ENST00000437659.1
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