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PRAC1 PRAC1 small nuclear protein [ Homo sapiens (human) ]

Gene ID: 84366, updated on 11-Jun-2021

Summary

Official Symbol
PRAC1provided by HGNC
Official Full Name
PRAC1 small nuclear proteinprovided by HGNC
Primary source
HGNC:HGNC:30591
See related
Ensembl:ENSG00000159182 MIM:609819
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRAC; C17orf92
Summary
This gene is reported to be specifically expressed in prostate, rectum and distal colon. Sequence analysis suggests that it may play a regulatory role in the nucleus. [provided by RefSeq, Jul 2008]
Expression
Biased expression in colon (RPKM 46.5) and prostate (RPKM 34.0) See more
Orthologs
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Genomic context

See PRAC1 in Genome Data Viewer
Location:
17q21.32
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (48721719..48722518, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46799081..46799880, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2086 Neighboring gene ribosomal protein L9 pseudogene 28 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene 2 Neighboring gene PRAC2 small nuclear protein Neighboring gene microRNA 3185 Neighboring gene homeobox B13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Clone Names

  • MGC32520

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
small nuclear protein PRAC1
Names
prostate cancer susceptibility candidate 1
prostate cancer susceptibility candidate protein 1
prostate, rectum and colon expressed gene protein
small nuclear protein PRAC

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032391.3NP_115767.1  small nuclear protein PRAC1

    See identical proteins and their annotated locations for NP_115767.1

    Status: REVIEWED

    Source sequence(s)
    AF331165, BC030950
    Consensus CDS
    CCDS11535.1
    UniProtKB/Swiss-Prot
    Q96KF2
    Related
    ENSP00000290294.3, ENST00000290294.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    48721719..48722518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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