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CAPNS2 calpain small subunit 2 [ Homo sapiens (human) ]

Gene ID: 84290, updated on 2-Mar-2021

Summary

Official Symbol
CAPNS2provided by HGNC
Official Full Name
calpain small subunit 2provided by HGNC
Primary source
HGNC:HGNC:16371
See related
Ensembl:ENSG00000256812 MIM:616767
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CSS2
Orthologs
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Genomic context

See CAPNS2 in Genome Data Viewer
Location:
16q12.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (55566684..55567687)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (55600596..55601599)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MMP2 antisense RNA 1 Neighboring gene matrix metallopeptidase 2 Neighboring gene lysophosphatidylcholine acyltransferase 2 Neighboring gene solute carrier family 6 member 2 Neighboring gene uncharacterized LOC105371280

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC12536, MGC14804

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-dependent cysteine-type endopeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
extracellular matrix disassembly TAS
Traceable Author Statement
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
calpain small subunit 2
Names
calcium-dependent protease small subunit 2
NP_115706.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032330.3NP_115706.1  calpain small subunit 2

    See identical proteins and their annotated locations for NP_115706.1

    Status: VALIDATED

    Source sequence(s)
    BC005397, BC006000
    Consensus CDS
    CCDS54010.1
    UniProtKB/Swiss-Prot
    Q96L46
    Related
    ENSP00000400882.2, ENST00000457326.3
    Conserved Domains (1) summary
    cd16188
    Location:80248
    EFh_PEF_CPNS1_2; Penta-EF hand, calcium binding motifs, found in calcium-dependent protease small subunit CAPNS1 and CAPNS2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    55566684..55567687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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