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ANKRD20A1 ankyrin repeat domain 20 family member A1 [ Homo sapiens (human) ]

Gene ID: 84210, updated on 3-Mar-2026
Official Symbol
ANKRD20A1provided by HGNC
Official Full Name
ankyrin repeat domain 20 family member A1provided by HGNC
Primary source
HGNC:HGNC:23665
See related
Ensembl:ENSG00000260691 AllianceGenome:HGNC:23665
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ANKRD20A
Summary
Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Broad expression in testis (RPKM 5.3), lung (RPKM 0.9) and 14 other tissues See more
Orthologs
all
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See ANKRD20A1 in Genome Data Viewer
Location:
9q21.11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (67858931..67902394)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (43016231..43059647, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (67926377..67969840)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900280 Neighboring gene uncharacterized LOC101928608 Neighboring gene RNA, U6 small nuclear 368, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:70837488-70837989 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:70895397-70895980 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:70895981-70896564 Neighboring gene uncharacterized LOC124902173 Neighboring gene Zn regulated GTPase metalloprotein activator 1C Neighboring gene forkhead box D4 like 3

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behçet's disease. Vural B, et al. Clin Exp Rheumatol, 2009 Mar-Apr. PMID 19796537
  2. DNA sequence and analysis of human chromosome 9. Humphray SJ, et al. Nature, 2004 May 27. PMID 15164053, Free PMC Article
  3. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. Simpson JC, et al. EMBO Rep, 2000 Sep. PMID 11256614, Free PMC Article
  4. The LIFEdb database in 2006. Mehrle A, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381901, Free PMC Article
  5. From ORFeome to biology: a functional genomics pipeline. Wiemann S, et al. Genome Res, 2004 Oct. PMID 15489336, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • DKFZp434A171

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  
Preferred Names
ankyrin repeat domain-containing protein 20A1
Names
ankyrin repeat domain 20A
epididymis secretory sperm binding protein

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032250.5 → NP_115626.2  ankyrin repeat domain-containing protein 20A1

    See identical proteins and their annotated locations for NP_115626.2

    Status: VALIDATED

    Source sequence(s)
    BX649567
    Consensus CDS
    CCDS6620.1
    UniProtKB/Swiss-Prot
    Q5SQ80, Q5TYW2, Q5VUR7, Q9H0H6
    UniProtKB/TrEMBL
    A0A384NKR9, B2RTT7
    Related
    ENSP00000477695.1, ENST00000562196.6
    Conserved Domains (4) summary
    cd00204
    Location:61 → 186
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:99 → 130
    ANK; ANK repeat [structural motif]
    pfam09731
    Location:291 → 690
    Mitofilin; Mitochondrial inner membrane protein
    pfam14915
    Location:514 → 805
    CCDC144C; CCDC144C protein coiled-coil region

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    67858931..67902394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    43016231..43059647 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5TYW2.1 GenPept UniProtKB/Swiss-Prot:Q5TYW2

Gene LinkOut

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