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USP48 ubiquitin specific peptidase 48 [ Homo sapiens (human) ]

Gene ID: 84196, updated on 2-Nov-2024

Summary

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Official Symbol
USP48provided by HGNC
Official Full Name
ubiquitin specific peptidase 48provided by HGNC
Primary source
HGNC:HGNC:18533
See related
Ensembl:ENSG00000090686 MIM:617445; AllianceGenome:HGNC:18533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
USP31; DFNA85; RAP1GA1
Summary
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in adrenal (RPKM 9.7), lymph node (RPKM 7.9) and 25 other tissues See more
Orthologs
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Genomic context

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See USP48 in Genome Data Viewer
Location:
1p36.12
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (21678298..21783149, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (21502254..21607091, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (22004791..22109642, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21917321-21917860 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21917861-21918399 Neighboring gene long intergenic non-protein coding RNA 2596 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:21928741-21928970 Neighboring gene Sharpr-MPRA regulatory region 12165 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21937517-21938264 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:21939576-21939868 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21945135-21945976 Neighboring gene RAP1 GTPase activating protein Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21958265-21959233 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21960338-21961086 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21961087-21961835 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:21966135-21966964 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21977615-21978365 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 384 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 385 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:21992551-21993051 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 387 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:21996570-21997769 Neighboring gene uncharacterized LOC124904736 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 388 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 336 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:22099067-22099566 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 337 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:22108688-22109459 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:22109460-22110230 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:22112153-22112327 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:22137244-22137394 Neighboring gene Sharpr-MPRA regulatory region 6146 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 390 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:22148116-22148982 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:22168222-22168722 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:22170194-22170694 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:22174882-22175382 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:22175383-22175883 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:22178409-22179608 Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:22191053-22191858 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:22191859-22192664 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 341 Neighboring gene ribosomal protein L21 pseudogene 29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Regulation of ubiquitin-dependent processes by deubiquitinating enzymes. Wilkinson KD. FASEB J, 1997 Dec. PMID 9409543
  2. Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis. Lockhart PJ, et al. DNA Seq, 2004 Feb. PMID 15354349
  3. Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48. Velimezi G, et al. Nat Commun, 2018 Jun 11. PMID 29891926, Free PMC Article
  4. USP48 Sustains Chemoresistance and Metastasis in Ovarian Cancer. Lei X, et al. Curr Cancer Drug Targets, 2020. PMID 32359336
  5. Identification of recurrent USP48 and BRAF mutations in Cushing's disease. Chen J, et al. Nat Commun, 2018 Aug 9. PMID 30093687, Free PMC Article

See all (76) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. USP48 deubiquitination stabilizes SLC1A5 to inhibit retinal pigment epithelium cell inflammation, oxidative stress and ferroptosis in the progression of diabetic retinopathy.
    Title: USP48 deubiquitination stabilizes SLC1A5 to inhibit retinal pigment epithelium cell inflammation, oxidative stress and ferroptosis in the progression of diabetic retinopathy.
  2. CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
    Title: CircUSP48 promotes malignant behavior by regulating CYR61 via miR-365 in osteosarcoma.
  3. USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection.
    Title: USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection.
  4. miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/beta-catenin signaling pathway via regulating USP48.
    Title: miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/β-catenin signaling pathway via regulating USP48.
  5. USP8, USP48, and BRAF mutations differ in their genotype-phenotype correlation in Asian Indian patients with Cushing's disease.
    Title: USP8, USP48, and BRAF mutations differ in their genotype-phenotype correlation in Asian Indian patients with Cushing's disease.
  6. USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization.
    Title: USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization.
  7. USP48 Governs Cell Cycle Progression by Regulating the Protein Level of Aurora B.
    Title: USP48 Governs Cell Cycle Progression by Regulating the Protein Level of Aurora B.
  8. USP48 Sustains Chemoresistance and Metastasis in Ovarian Cancer.
    Title: USP48 Sustains Chemoresistance and Metastasis in Ovarian Cancer.
  9. LINC00467 enhances head and neck squamous cell carcinoma progression and the epithelial-mesenchymal transition process via miR-299-5p/ubiquitin specific protease-48 axis.
    Title: LINC00467 enhances head and neck squamous cell carcinoma progression and the epithelial-mesenchymal transition process via miR-299-5p/ubiquitin specific protease-48 axis.
  10. USP48 pathogenic variants are relatively frequent in USP8 wild-type Cushing's disease tumors
    Title: Driver mutations in USP8 wild-type Cushing's disease.
Submit: New GeneRIF Correction See all GeneRIFs (21)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Hearing loss, autosomal dominant 85
MedGen: C5774302 OMIM: 620227 GeneReviews: Not available
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Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC14879, MGC132556, DKFZp762M1713

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables deubiquitinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of protein stability IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cilium IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 48
Names
deubiquitinating enzyme 48
ubiquitin specific protease 31
ubiquitin thioesterase 48
ubiquitin thiolesterase 48
ubiquitin-specific-processing protease 48
NP_001027902.1
NP_001317323.1
NP_001337093.1
NP_001337095.1
NP_001337096.1
NP_001337097.1
NP_115612.4
XP_006711018.1
XP_011540566.1
XP_011540569.1
XP_011540570.1
XP_047287982.1
XP_047287983.1
XP_047287985.1
XP_047287986.1
XP_047287987.1
XP_047287988.1
XP_047287989.1
XP_054195088.1
XP_054195089.1
XP_054195090.1
XP_054195091.1
XP_054195092.1
XP_054195093.1
XP_054195094.1
XP_054195095.1
XP_054195096.1
XP_054195097.1
XP_054195098.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_047203.1 RefSeqGene

    Range
    5051..109902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032730.3 → NP_001027902.1  ubiquitin carboxyl-terminal hydrolase 48 isoform b

    See identical proteins and their annotated locations for NP_001027902.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the coding region, compared to variant 1. The encoded isoform (b) is much shorter and has a distinct C-terminus compared to isoform a.
    Source sequence(s)
    BC067261, BM462540, CA436959
    Consensus CDS
    CCDS44084.1
    UniProtKB/Swiss-Prot
    Q86UV5
    Related
    ENSP00000406256.2, ENST00000421625.6
    Conserved Domains (1) summary
    cd02668
    Location:90 → 419
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

  2. NM_001330394.3 → NP_001317323.1  ubiquitin carboxyl-terminal hydrolase 48 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AF502942, AL359815, BC104896, BQ027743, DB134378
    Consensus CDS
    CCDS81277.1
    UniProtKB/TrEMBL
    B7ZKR8
    Related
    ENSP00000383157.1, ENST00000400301.5
    Conserved Domains (4) summary
    cd02668
    Location:90 → 419
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:89 → 418
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam06337
    Location:484 → 554
    DUSP; DUSP domain
    cl00155
    Location:909 → 983
    UBQ; Ubiquitin-like proteins

  3. NM_001350164.2 → NP_001337093.1  ubiquitin carboxyl-terminal hydrolase 48 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses an alternate in-frame splice site and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (d) has the same N- and C-termini, but is shorter compared to isoform a.
    Source sequence(s)
    AF502942, AK226150, AL359815, BQ027743, BQ220710, DB134378
    UniProtKB/TrEMBL
    B7ZKS3
    Conserved Domains (2) summary
    cd01795
    Location:862 → 968
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:90 → 418
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

  4. NM_001350166.2 → NP_001337095.1  ubiquitin carboxyl-terminal hydrolase 48 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) uses two alternate in-frame splice sites in the central coding region, compared to variant 1. The encoded isoform (e) has the same N- and C-termini, but is two aa shorter than isoform a.
    Source sequence(s)
    AK074247, AL359815, AL834375, BC104896, BQ027743, BQ220710, DB134378
    UniProtKB/TrEMBL
    B7ZKS3
    Conserved Domains (3) summary
    cd01795
    Location:927 → 1033
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:90 → 418
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam06337
    Location:483 → 553
    DUSP; DUSP domain

  5. NM_001350167.2 → NP_001337096.1  ubiquitin carboxyl-terminal hydrolase 48 isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (f) has the same N- and C-termini, but is one aa shorter than isoform a. This isoform is the same length as isoform g, but contains a unique sequence.
    Source sequence(s)
    AL359815, AL834375, BC104896, BM928619, BQ027743, BQ220710, DB134378
    UniProtKB/TrEMBL
    B7ZKS3
    Related
    ENSP00000431949.1, ENST00000529637.5
    Conserved Domains (3) summary
    cd01795
    Location:928 → 1034
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:90 → 418
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam06337
    Location:483 → 553
    DUSP; DUSP domain

  6. NM_001350168.2 → NP_001337097.1  ubiquitin carboxyl-terminal hydrolase 48 isoform g

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (g) has the same N- and C-termini, but is one aa shorter than isoform a. This isoform is the same length as isoform f, but contains a unique sequence.
    Source sequence(s)
    AK074247, AL359815, AL834375, BC104896, BE378955, BQ027743, BQ220710, DB134378
    UniProtKB/TrEMBL
    B7ZKS3
    Conserved Domains (3) summary
    cd01795
    Location:928 → 1034
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:90 → 419
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam06337
    Location:484 → 554
    DUSP; DUSP domain

  7. NM_032236.8 → NP_115612.4  ubiquitin carboxyl-terminal hydrolase 48 isoform a

    See identical proteins and their annotated locations for NP_115612.4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AF502942, AL359815, BQ027743, DB134378
    Consensus CDS
    CCDS30623.1
    UniProtKB/Swiss-Prot
    B7ZKS7, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q86UV5, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0
    UniProtKB/TrEMBL
    B7ZKS3
    Related
    ENSP00000309262.9, ENST00000308271.14
    Conserved Domains (4) summary
    cd01795
    Location:929 → 1035
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:90 → 419
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:89 → 418
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam06337
    Location:484 → 554
    DUSP; DUSP domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    21678298..21783149 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047432030.1 → XP_047287986.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

  2. XM_047432026.1 → XP_047287982.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X1

  3. XM_047432029.1 → XP_047287985.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X4

  4. XM_047432031.1 → XP_047287987.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X7

  5. XM_006710955.5 → XP_006711018.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

    See identical proteins and their annotated locations for XP_006711018.1

    UniProtKB/TrEMBL
    B7ZKS3
    Conserved Domains (2) summary
    cd02668
    Location:90 → 419
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd01795
    Location:873 → 968
    Ubl_USP48; ubiquitin-like (Ubl) domain found in ubiquitin-specific-processing protease 48 (USP48) and similar proteins

  6. XM_047432027.1 → XP_047287983.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

  7. XM_011542264.2 → XP_011540566.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

    UniProtKB/TrEMBL
    B7ZKS3
    Conserved Domains (5) summary
    cd01795
    Location:862 → 968
    USP48_C; USP ubiquitin-specific protease
    cd02668
    Location:23 → 352
    Peptidase_C19L; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:22 → 351
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam06337
    Location:417 → 487
    DUSP; DUSP domain
    cl12116
    Location:670 → 713
    DUSP; DUSP domain

  8. XM_011542267.4 → XP_011540569.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X10

    See identical proteins and their annotated locations for XP_011540569.1

    UniProtKB/TrEMBL
    A0A0A0MRS6
    Conserved Domains (3) summary
    cd01795
    Location:515 → 621
    USP48_C; USP ubiquitin-specific protease
    pfam06337
    Location:70 → 140
    DUSP; DUSP domain
    cl12116
    Location:323 → 366
    DUSP; DUSP domain

  9. XM_011542268.3 → XP_011540570.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X10

    See identical proteins and their annotated locations for XP_011540570.1

    UniProtKB/TrEMBL
    A0A0A0MRS6
    Conserved Domains (3) summary
    cd01795
    Location:515 → 621
    USP48_C; USP ubiquitin-specific protease
    pfam06337
    Location:70 → 140
    DUSP; DUSP domain
    cl12116
    Location:323 → 366
    DUSP; DUSP domain

  10. XM_047432033.1 → XP_047287989.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X9

  11. XM_047432032.1 → XP_047287988.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X8

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    21502254..21607091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054339118.1 → XP_054195093.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X6

  2. XM_054339113.1 → XP_054195088.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X1

  3. XM_054339116.1 → XP_054195091.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X4

  4. XM_054339119.1 → XP_054195094.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X7

  5. XM_054339115.1 → XP_054195090.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X3

  6. XM_054339114.1 → XP_054195089.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X2

  7. XM_054339117.1 → XP_054195092.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X5

  8. XM_054339122.1 → XP_054195097.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X10

  9. XM_054339123.1 → XP_054195098.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X10

  10. XM_054339121.1 → XP_054195096.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X9

  11. XM_054339120.1 → XP_054195095.1  ubiquitin carboxyl-terminal hydrolase 48 isoform X8

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86UV5.1 GenPept UniProtKB/Swiss-Prot:Q86UV5

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