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TKTL2 transketolase like 2 [ Homo sapiens (human) ]

Gene ID: 84076, updated on 18-Aug-2020

Summary

Official Symbol
TKTL2provided by HGNC
Official Full Name
transketolase like 2provided by HGNC
Primary source
HGNC:HGNC:25313
See related
Ensembl:ENSG00000151005
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs

Genomic context

See TKTL2 in Genome Data Viewer
Location:
4q32.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (163471095..163473754, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (164392245..164395047, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y1 Neighboring gene neuropeptide Y receptor Y5 Neighboring gene ribosomal protein L35a pseudogene 12 Neighboring gene CRISPRi-validated cis-regulatory element chr4.3253 Neighboring gene translation machinery associated 16 homolog

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ32975, DKFZp434L1717

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
thiamine pyrophosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transketolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
transketolase-like protein 2
Names
testis tissue sperm-binding protein Li 39a
NP_115512.3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032136.5NP_115512.3  transketolase-like protein 2

    See identical proteins and their annotated locations for NP_115512.3

    Status: VALIDATED

    Source sequence(s)
    AL136779, DB095901
    Consensus CDS
    CCDS3805.1
    UniProtKB/Swiss-Prot
    Q9H0I9
    UniProtKB/TrEMBL
    A0A140VKC2
    Related
    ENSP00000280605.3, ENST00000280605.5
    Conserved Domains (4) summary
    cd07033
    Location:323477
    TPP_PYR_DXS_TK_like; Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins
    PRK05899
    Location:9620
    PRK05899; transketolase; Reviewed
    cd02012
    Location:21269
    TPP_TK; Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the ...
    pfam02780
    Location:494616
    Transketolase_C; Transketolase, C-terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    163471095..163473754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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