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OR1A1 olfactory receptor family 1 subfamily A member 1 [ Homo sapiens (human) ]

Gene ID: 8383, updated on 13-May-2022

Summary

Official Symbol
OR1A1provided by HGNC
Official Full Name
olfactory receptor family 1 subfamily A member 1provided by HGNC
Primary source
HGNC:HGNC:8179
See related
Ensembl:ENSG00000172146 MIM:618046; AllianceGenome:HGNC:8179
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR17-7
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR1A1 in Genome Data Viewer
Location:
17p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (3207667..3218896)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (3095937..3107165)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (3110961..3122190)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100288728 Neighboring gene olfactory receptor family 1 subfamily P member 1 (gene/pseudogene) Neighboring gene olfactory receptor family 1 subfamily A member 2 Neighboring gene olfactory receptor family 1 subfamily D member 4 Neighboring gene olfactory receptor family 1 subfamily D member 3 pseudogene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 1A1
Names
olfactory receptor 17-7
olfactory receptor OR17-11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386104.1NP_001373033.1  olfactory receptor 1A1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC090282
    Related
    ENSP00000492897.1, ENST00000641322.1
    Conserved Domains (1) summary
    cd15235
    Location:24299
    7tmA_OR1A-like; olfactory receptor subfamily 1A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. NM_014565.3NP_055380.2  olfactory receptor 1A1

    See identical proteins and their annotated locations for NP_055380.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC090282
    Consensus CDS
    CCDS11022.1
    UniProtKB/Swiss-Prot
    Q9P1Q5
    UniProtKB/TrEMBL
    A0A126GWA2
    Related
    ENSP00000493179.1, ENST00000641732.2
    Conserved Domains (1) summary
    cd15235
    Location:24299
    7tmA_OR1A-like; olfactory receptor subfamily 1A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    3207667..3218896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    3095937..3107165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)