U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cnnm1 cyclin M1 [ Mus musculus (house mouse) ]

Gene ID: 83674, updated on 5-Mar-2024

Summary

Official Symbol
Cnnm1provided by MGI
Official Full Name
cyclin M1provided by MGI
Primary source
MGI:MGI:1891366
See related
Ensembl:ENSMUSG00000025189 AllianceGenome:MGI:1891366
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Acdp1; CLP-1
Summary
Predicted to enable transmembrane transporter activity. Predicted to act upstream of or within ion transport. Located in dendrite; neuronal cell body; and plasma membrane. Orthologous to human CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 15.2), cortex adult (RPKM 9.8) and 7 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Cnnm1 in Genome Data Viewer
Location:
19 C3; 19 36.67 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (43427508..43485649)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (43439069..43497210)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene heparanase 2 Neighboring gene leucine zipper transcription factor-like 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_46194 Neighboring gene predicted gene, 38568 Neighboring gene STARR-seq mESC enhancer starr_46196 Neighboring gene STARR-positive B cell enhancer mm9_chr19:43592413-43592714 Neighboring gene STARR-positive B cell enhancer ABC_E1525 Neighboring gene STARR-positive B cell enhancer ABC_E1213 Neighboring gene translocase of inner mitochondrial membrane 23 homolog pseudogene Neighboring gene glutamic-oxaloacetic transaminase 1, soluble

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in magnesium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
metal transporter CNNM1
Names
ancient conserved domain protein 1
ancient conserved domain-containing protein 1
cyclin-like protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001373992.1NP_001360921.1  metal transporter CNNM1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC140375
    Consensus CDS
    CCDS89394.1
    UniProtKB/TrEMBL
    A0A286YDL2
    Related
    ENSMUSP00000153472.2, ENSMUST00000223787.2
    Conserved Domains (1) summary
    COG1253
    Location:251553
    TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]
  2. NM_001424972.1NP_001411901.1  metal transporter CNNM1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC140375
  3. NM_031396.3NP_113573.2  metal transporter CNNM1 isoform 2

    See identical proteins and their annotated locations for NP_113573.2

    Status: VALIDATED

    Source sequence(s)
    AC140375, AF202994, EF041508
    Consensus CDS
    CCDS50442.1
    UniProtKB/Swiss-Prot
    Q0GA42, Q9JIQ6
    Related
    ENSMUSP00000131830.2, ENSMUST00000165311.3
    Conserved Domains (1) summary
    COG1253
    Location:251553
    TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    43427508..43485649
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527480.5XP_006527543.1  metal transporter CNNM1 isoform X1

    Conserved Domains (1) summary
    COG1253
    Location:251553
    TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]
  2. XM_006527482.5XP_006527545.1  metal transporter CNNM1 isoform X2

    Conserved Domains (1) summary
    COG1253
    Location:251553
    TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]
  3. XM_036161732.1XP_036017625.1  metal transporter CNNM1 isoform X3

    Conserved Domains (1) summary
    COG1253
    Location:251553
    TlyC; Hemolysin or related protein, contains CBS domains [General function prediction only]

RNA

  1. XR_004940187.1 RNA Sequence