Format

Send to:

Choose Destination

TEKT1 tektin 1 [ Homo sapiens (human) ]

Gene ID: 83659, updated on 23-Nov-2021

Summary

Official Symbol
TEKT1provided by HGNC
Official Full Name
tektin 1provided by HGNC
Primary source
HGNC:HGNC:15534
See related
Ensembl:ENSG00000167858 MIM:609002
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 17.1) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TEKT1 in Genome Data Viewer
Location:
17p13.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (6797993..6831734, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (6701312..6735048, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene F-box protein 39 Neighboring gene GATA motif-containing MPRA enhancer 34 Neighboring gene arachidonate 12-lipoxygenase pseudogene 2 Neighboring gene Spi-C transcription factor (Spi-1/PU.1 related) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053285.2NP_444515.1  tektin-1

    See identical proteins and their annotated locations for NP_444515.1

    Status: REVIEWED

    Source sequence(s)
    AC034305, BC014599
    Consensus CDS
    CCDS11083.1
    UniProtKB/Swiss-Prot
    Q969V4
    Related
    ENSP00000341346.2, ENST00000338694.7
    Conserved Domains (1) summary
    pfam03148
    Location:16395
    Tektin; Tektin family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    6797993..6831734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524027.3XP_011522329.1  tektin-1 isoform X1

    Conserved Domains (1) summary
    pfam03148
    Location:16286
    Tektin; Tektin family
Support Center