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PAS_chr2-1_0048 Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u [ Komagataella phaffii GS115 ]

Gene ID: 8198167, updated on 23-Nov-2023

Summary

Gene symbol
PAS_chr2-1_0048
Gene description
Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u
Locus tag
PAS_chr2-1_0048
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Komagataella phaffii GS115 (strain: GS115)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella
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Genomic context

Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_012964.1 (79295..81538)

Chromosome 2 - NC_012964.1Genomic Context describing neighboring genes Neighboring gene Hypothetical protein Neighboring gene Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to urac Neighboring gene Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secre Neighboring gene uncharacterized protein

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ferric-chelate reductase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in copper ion import IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular iron ion homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_012964.1 Reference assembly

    Range
    79295..81538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002490883.1XP_002490928.1  Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to u [Komagataella phaffii GS115]

    See identical proteins and their annotated locations for XP_002490928.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    C4QZH4, F2QU57
    Conserved Domains (3) summary
    cd06186
    Location:449616
    NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
    pfam01794
    Location:279391
    Ferric_reduct; Ferric reductase like transmembrane component
    cl23719
    Location:544725
    NAD_binding_1; Oxidoreductase NAD-binding domain