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OR2B2 olfactory receptor family 2 subfamily B member 2 [ Homo sapiens (human) ]

Gene ID: 81697, updated on 5-Jan-2022

Summary

Official Symbol
OR2B2provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily B member 2provided by HGNC
Primary source
HGNC:HGNC:13966
See related
Ensembl:ENSG00000168131
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2B9; OR6-1; OR2B2Q; hs6M1-10; dJ193B12.4
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2B2 in Genome Data Viewer
Location:
6p22.1
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (27911185..27912396, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (27878963..27880174, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr6.1315 Neighboring gene tRNA-iMet (anticodon CAT) 1-7 Neighboring gene tRNA-Gly (anticodon GCC) 2-3 Neighboring gene olfactory receptor family 2 subfamily W member 6 pseudogene Neighboring gene olfactory receptor family 2 subfamily B member 6

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2B2
Names
olfactory receptor 2B9
olfactory receptor 6-1
olfactory receptor OR6-2
olfactory receptor, family 2, subfamily B, member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033057.2NP_149046.2  olfactory receptor 2B2

    See identical proteins and their annotated locations for NP_149046.2

    Status: VALIDATED

    Source sequence(s)
    BC136901
    Consensus CDS
    CCDS4641.1
    UniProtKB/Swiss-Prot
    Q9GZK3
    UniProtKB/TrEMBL
    A0A126GWD0
    Related
    ENSP00000304419.2, ENST00000303324.4
    Conserved Domains (1) summary
    cd15432
    Location:25301
    7tmA_OR2B2-like; olfactory receptor subfamily 2B2 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    27911185..27912396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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