Format

Send to:

Choose Destination

OR5V1 olfactory receptor family 5 subfamily V member 1 [ Homo sapiens (human) ]

Gene ID: 81696, updated on 11-Jun-2021

Summary

Official Symbol
OR5V1provided by HGNC
Official Full Name
olfactory receptor family 5 subfamily V member 1provided by HGNC
Primary source
HGNC:HGNC:13972
See related
Ensembl:ENSG00000243729
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
6M1-21; hs6M1-21
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR5V1 in Genome Data Viewer
Location:
6p22.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (29353749..29455207, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (29321526..29336642, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375005 Neighboring gene olfactory receptor family 14 subfamily J member 1 Neighboring gene DEAD-box helicase 6 pseudogene 1 Neighboring gene olfactory receptor family 12 subfamily D member 3 Neighboring gene olfactory receptor family 12 subfamily D member 2 Neighboring gene olfactory receptor family 12 subfamily D member 1 (gene/pseudogene) Neighboring gene olfactory receptor family 11 subfamily A member 1 Neighboring gene uncharacterized LOC105379641 Neighboring gene olfactory receptor family 10 subfamily C member 1 Neighboring gene olfactory receptor family 2 subfamily H member 1 Neighboring gene ubiquitin D pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Common variation contributes to the genetic architecture of social communication traits.
GeneReviews: Not available

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 5V1
Names
olfactory receptor OR6-26

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030876.6NP_110503.3  olfactory receptor 5V1

    See identical proteins and their annotated locations for NP_110503.3

    Status: VALIDATED

    Source sequence(s)
    AL662781
    Consensus CDS
    CCDS4657.1
    UniProtKB/Swiss-Prot
    Q9UGF6
    UniProtKB/TrEMBL
    A0A126GV99
    Related
    ENSP00000493269.1, ENST00000641768.1
    Conserved Domains (1) summary
    cd15231
    Location:25301
    7tmA_OR5V1-like; olfactory receptor subfamily 5V1 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    29353749..29455207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024446562.1XP_024302330.1  olfactory receptor 5V1 isoform X1

    Conserved Domains (1) summary
    cd15231
    Location:25301
    7tmA_OR5V1-like; olfactory receptor subfamily 5V1 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    840339..855469 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_4

Genomic

  1. NT_167246.2 Reference GRCh38.p13 ALT_REF_LOCI_4

    Range
    619353..634153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p13 ALT_REF_LOCI_5

    Range
    619575..634376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_7

Genomic

  1. NT_167249.2 Reference GRCh38.p13 ALT_REF_LOCI_7

    Range
    663200..677991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center