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PF3D7_1468700 eukaryotic initiation factor 4A [ Plasmodium falciparum 3D7 ]

Gene ID: 812237, updated on 12-Sep-2024

Summary

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Gene symbol
PF3D7_1468700
Gene description
eukaryotic initiation factor 4A
Locus tag
PF3D7_1468700
See related
PlasmoDB:PF3D7_1468700; VEuPathDB:PF3D7_1468700
Gene type
protein coding
RNA name
eukaryotic initiation factor 4A
RefSeq status
PROVISIONAL
Organism
Plasmodium falciparum 3D7 (isolate: 3D7)
Lineage
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
Orthologs
all
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Genomic context

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See PF3D7_1468700 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Sequence:
Chromosome: 14; NC_037283.1 (2825370..2826918)

Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene derlin-1 Neighboring gene aminophospholipid transporter, putative Neighboring gene splicing factor U2AF large subunit, putative Neighboring gene zinc finger protein, putative

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037283.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enhanced purification and characterization of the PfeIF4A (PfH45) helicase from Plasmodium falciparum using a codon-optimised clone. Evans L, et al. Protein Expr Purif, 2012 Sep. PMID 22750398
  2. Isolation and functional characterization of eIF4F components and poly(A)-binding protein from Plasmodium falciparum. Tuteja R, et al. Parasitol Int, 2009 Dec. PMID 19751846
  3. Food vacuole proteome of the malarial parasite Plasmodium falciparum. Lamarque M, et al. Proteomics Clin Appl, 2008 Sep. PMID 21136929
  4. Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome. Abdi A, et al. Wellcome Open Res, 2017. PMID 28944300, Free PMC Article
  5. Functional Characterization of the m(6)A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. Sinha A, et al. mBio, 2021 Apr 27. PMID 33906926, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by GeneDB

Function Evidence Code Pubs
enables 3'-5' DNA/RNA helicase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding HDA PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular vesicle HDA PubMed 
located_in food vacuole HDA PubMed 
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
eukaryotic initiation factor 4A
XP_001348829.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_037283.1 Reference assembly

    Range
    2825370..2826918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001348793.1 → XP_001348829.1  eukaryotic initiation factor 4A [Plasmodium falciparum 3D7]

    See identical proteins and their annotated locations for XP_001348829.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A024UY98, A0A024WIB5, A0A024X0H4, A0A0L0CYX2, A0A0L1IE72, A0A0L7K5Y6, A0A0L7M3H6, A0A2I0C1J7, Q2PZH3, Q8IKF0, W7FD46, W7FQU2, W7JPL6
    Conserved Domains (1) summary
    PTZ00424
    Location:1 → 398
    PTZ00424; helicase 45; Provisional
Nucleotide Protein
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