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OR11H1 olfactory receptor family 11 subfamily H member 1 [ Homo sapiens (human) ]

Gene ID: 81061, updated on 26-Oct-2022

Summary

Official Symbol
OR11H1provided by HGNC
Official Full Name
olfactory receptor family 11 subfamily H member 1provided by HGNC
Primary source
HGNC:HGNC:15404
See related
Ensembl:ENSG00000130538 AllianceGenome:HGNC:15404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR22-1; OR11H12
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR11H1 in Genome Data Viewer
Location:
22q11.1
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (15528192..15529139)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (16102207..16103154)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (16448824..16449771, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene BCL2 interacting protein 3 pseudogene 2 Neighboring gene YME1L1 pseudogene 1 Neighboring gene rho GTPase-activating protein 42-like Neighboring gene ARHGAP42 pseudogene 3 Neighboring gene fatty acyl-CoA reductase 2 pseudogene Neighboring gene ubiquitin specific peptidase 10 pseudogene

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 11H1
Names
olfactory receptor OR22-1
seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005239.2NP_001005239.2  olfactory receptor 11H1

    Status: VALIDATED

    Source sequence(s)
    AP000534
    Consensus CDS
    CCDS74807.2
    UniProtKB/TrEMBL
    A0A126GWF9
    Related
    ENSP00000495403.1, ENST00000643195.1
    Conserved Domains (1) summary
    cd15913
    Location:29298
    7tmA_OR11G-like; olfactory receptor OR11G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    15528192..15529139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    16102207..16103154
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)