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CEP44 centrosomal protein 44 [ Homo sapiens (human) ]

Gene ID: 80817, updated on 12-Oct-2019

Summary

Official Symbol
CEP44provided by HGNC
Official Full Name
centrosomal protein 44provided by HGNC
Primary source
HGNC:HGNC:29356
See related
Ensembl:ENSG00000164118
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PS1TP3; KIAA1712
Expression
Ubiquitous expression in testis (RPKM 3.4), endometrium (RPKM 3.1) and 25 other tissues See more
Orthologs

Genomic context

See CEP44 in Genome Data Viewer
Location:
4q34.1
Exon count:
14
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (174283677..174334355)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (175204828..175255506)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2268 Neighboring gene F-box protein 8 Neighboring gene uncharacterized LOC105377547 Neighboring gene microRNA 4276

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1712

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
midbody TAS
Traceable Author Statement
more info
PubMed 
spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
centrosomal protein of 44 kDa
Names
HBV PreS1-transactivated protein 3
centrosomal protein 44kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040157.3NP_001035247.1  centrosomal protein of 44 kDa isoform a

    See identical proteins and their annotated locations for NP_001035247.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (a).
    Source sequence(s)
    AC097653, AY426674, DA347369
    Consensus CDS
    CCDS34106.1
    UniProtKB/Swiss-Prot
    Q9C0F1
    Related
    ENSP00000423153.1, ENST00000503780.6
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  2. NM_001145314.1NP_001138786.1  centrosomal protein of 44 kDa isoform b

    See identical proteins and their annotated locations for NP_001138786.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3' exon, compared to variant 1. The resulting protein (isoform b) has a longer and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC116616, AK094961, AL699124
    Consensus CDS
    CCDS47163.1
    UniProtKB/Swiss-Prot
    Q9C0F1
    Related
    ENSP00000389427.2, ENST00000457424.6
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    174283677..174334355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011532286.2XP_011530588.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_011530588.1

    UniProtKB/Swiss-Prot
    Q9C0F1
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  2. XM_017008656.1XP_016864145.1  centrosomal protein of 44 kDa isoform X3

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  3. XM_024454229.1XP_024309997.1  centrosomal protein of 44 kDa isoform X1

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  4. XM_024454233.1XP_024310001.1  centrosomal protein of 44 kDa isoform X2

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  5. XM_024454236.1XP_024310004.1  centrosomal protein of 44 kDa isoform X4

  6. XM_011532287.2XP_011530589.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_011530589.1

    UniProtKB/Swiss-Prot
    Q9C0F1
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  7. XM_017008655.1XP_016864144.1  centrosomal protein of 44 kDa isoform X2

    UniProtKB/Swiss-Prot
    Q9C0F1
    Related
    ENSP00000296519.4, ENST00000296519.6
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  8. XM_011532285.2XP_011530587.1  centrosomal protein of 44 kDa isoform X1

    See identical proteins and their annotated locations for XP_011530587.1

    UniProtKB/Swiss-Prot
    Q9C0F1
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  9. XM_017008654.1XP_016864143.1  centrosomal protein of 44 kDa isoform X2

    UniProtKB/Swiss-Prot
    Q9C0F1
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  10. XM_017008657.1XP_016864146.1  centrosomal protein of 44 kDa isoform X3

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  11. XM_024454232.1XP_024310000.1  centrosomal protein of 44 kDa isoform X2

    Related
    ENSP00000380009.3, ENST00000396791.7
    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  12. XM_024454234.1XP_024310002.1  centrosomal protein of 44 kDa isoform X3

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  13. XM_024454231.1XP_024309999.1  centrosomal protein of 44 kDa isoform X1

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  14. XM_024454230.1XP_024309998.1  centrosomal protein of 44 kDa isoform X1

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2
  15. XM_024454235.1XP_024310003.1  centrosomal protein of 44 kDa isoform X3

    Conserved Domains (2) summary
    pfam15007
    Location:5131
    CEP44; Centrosomal spindle body, CEP44
    pfam15688
    Location:282356
    NRIP1_repr_2; Nuclear receptor-interacting protein 1 repression 2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_030633.1: Suppressed sequence

    Description
    NM_030633.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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