Format

Send to:

Choose Destination

NAA50 N-alpha-acetyltransferase 50, NatE catalytic subunit [ Homo sapiens (human) ]

Gene ID: 80218, updated on 23-Nov-2021

Summary

Official Symbol
NAA50provided by HGNC
Official Full Name
N-alpha-acetyltransferase 50, NatE catalytic subunitprovided by HGNC
Primary source
HGNC:HGNC:29533
See related
Ensembl:ENSG00000121579 MIM:610834
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SAN; MAK3; NAT5; NAT13; NAT5P; NAT13P; hNaa50p
Expression
Ubiquitous expression in esophagus (RPKM 21.2), fat (RPKM 20.2) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See NAA50 in Genome Data Viewer
Location:
3q13.31
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (113716458..113746249, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (113435305..113465096, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 767, pseudogene Neighboring gene upstream transcription factor family member 3 Neighboring gene ATPase H+ transporting V1 subunit A Neighboring gene GRAM domain containing 1C Neighboring gene ribosomal protein S10 pseudogene 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
GeneReviews: Not available

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13194

Gene Ontology Provided by GOA

Component Evidence Code Pubs
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NatA complex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular exosome HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
N-alpha-acetyltransferase 50
Names
N-acetyltransferase 13 (GCN5-related)
N-acetyltransferase 5
N-acetyltransferase san homolog
N-epsilon-acetyltransferase 50
natE catalytic subunit
NP_001295374.1
NP_079422.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308445.2NP_001295374.1  N-alpha-acetyltransferase 50 isoform 2

    See identical proteins and their annotated locations for NP_001295374.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. It encodes isoform 2 which is shorter compared to isoform 1.
    Source sequence(s)
    AC108693, AL601126, BX102492
    Consensus CDS
    CCDS77791.1
    UniProtKB/TrEMBL
    E7EQ69
    Related
    ENSP00000417837.1, ENST00000493900.5
    Conserved Domains (1) summary
    COG0456
    Location:9144
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
  2. NM_025146.4NP_079422.1  N-alpha-acetyltransferase 50 isoform 1

    See identical proteins and their annotated locations for NP_079422.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC108693, AW954963, BC012731, BM831426, BX102492, DA408894, DA599265, DB096143, DB198553, H15889, H39948, HX784836
    Consensus CDS
    CCDS2975.1
    UniProtKB/Swiss-Prot
    Q9GZZ1
    Related
    ENSP00000240922.2, ENST00000240922.8
    Conserved Domains (1) summary
    COG0456
    Location:10145
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    113716458..113746249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center