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TEDC2 tubulin epsilon and delta complex 2 [ Homo sapiens (human) ]

Gene ID: 80178, updated on 5-Aug-2022

Summary

Official Symbol
TEDC2provided by HGNC
Official Full Name
tubulin epsilon and delta complex 2provided by HGNC
Primary source
HGNC:HGNC:25849
See related
Ensembl:ENSG00000162062 AllianceGenome:HGNC:25849
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C16orf59
Summary
Predicted to be involved in positive regulation of smoothened signaling pathway. Predicted to be located in centriole and cilium. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 2.6), bone marrow (RPKM 1.5) and 19 other tissues See more
Orthologs
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Genomic context

See TEDC2 in Genome Data Viewer
Location:
16p13.3
Exon count:
10
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (2460109..2464963)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (2482238..2487092)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (2510110..2514964)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene cyclin F Neighboring gene microRNA 6767 Neighboring gene uncharacterized LOC105371050 Neighboring gene TEDC2 antisense RNA 1 Neighboring gene microRNA 6768 Neighboring gene netrin 3 Neighboring gene TBC1 domain family member 24

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13909

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of smoothened signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in centriole ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tubulin epsilon and delta complex protein 2
Names
uncharacterized protein C16orf59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025108.3NP_079384.2  tubulin epsilon and delta complex protein 2

    See identical proteins and their annotated locations for NP_079384.2

    Status: VALIDATED

    Source sequence(s)
    AC106820, AL559561, BC018719
    Consensus CDS
    CCDS10468.2
    UniProtKB/Swiss-Prot
    Q7L2K0, Q9H872
    Related
    ENSP00000355022.4, ENST00000361837.9
    Conserved Domains (1) summary
    pfam15764
    Location:148431
    DUF4693; Domain of unknown function (DUF4693)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    2460109..2464963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522667.2XP_011520969.1  tubulin epsilon and delta complex protein 2 isoform X1

    Conserved Domains (1) summary
    pfam15764
    Location:115398
    DUF4693; Domain of unknown function (DUF4693)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    2482238..2487092
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)