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VCPIP1 valosin containing protein interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 80124, updated on 23-Nov-2021

Summary

Official Symbol
VCPIP1provided by HGNC
Official Full Name
valosin containing protein interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:30897
See related
Ensembl:ENSG00000175073 MIM:611745
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DUBA3; VCIP135
Expression
Ubiquitous expression in bone marrow (RPKM 10.6), spleen (RPKM 6.5) and 25 other tissues See more
Orthologs
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Genomic context

See VCPIP1 in Genome Data Viewer
Location:
8q13.1
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (66628487..66667231, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (67540722..67579466, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene MYB proto-oncogene like 1 Neighboring gene uncharacterized LOC105375884 Neighboring gene C8orf44-SGK3 readthrough Neighboring gene chromosome 8 open reading frame 44 Neighboring gene serum/glucocorticoid regulated kinase family member 3 Neighboring gene pituitary tumor-transforming 3, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23132, FLJ60694, KIAA1850, DKFZp686G038

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables thiol-dependent deubiquitinase IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables thiol-dependent deubiquitinase IDA
Inferred from Direct Assay
more info
PubMed 
enables thiol-dependent deubiquitinase ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in Golgi reassembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to DNA damage stimulus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in endoplasmic reticulum membrane fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in protein K11-linked deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein K11-linked deubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein K48-linked deubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein K48-linked deubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein deubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein-DNA covalent cross-linking repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of protein localization to chromatin IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi stack IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 
located_in endoplasmic reticulum lumen TAS
Traceable Author Statement
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
deubiquitinating protein VCPIP1
Names
VCP/p47 complex-interacting 135-kDa protein
deubiquitinating protein VCIP135
valosin-containing protein p97/p47 complex-interacting protein 1
valosin-containing protein p97/p47 complex-interacting protein p135
NP_079330.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025054.5NP_079330.2  deubiquitinating protein VCPIP1

    See identical proteins and their annotated locations for NP_079330.2

    Status: VALIDATED

    Source sequence(s)
    AC090154
    Consensus CDS
    CCDS6192.1
    UniProtKB/Swiss-Prot
    Q96JH7
    Related
    ENSP00000309031.4, ENST00000310421.5
    Conserved Domains (1) summary
    cl19932
    Location:215355
    OTU; OTU-like cysteine protease

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    66628487..66667231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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