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NRSN2 neurensin 2 [ Homo sapiens (human) ]

Gene ID: 80023, updated on 23-Nov-2021

Summary

Official Symbol
NRSN2provided by HGNC
Official Full Name
neurensin 2provided by HGNC
Primary source
HGNC:HGNC:16229
See related
Ensembl:ENSG00000125841 MIM:610666
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf98; dJ1103G7.6
Expression
Broad expression in brain (RPKM 20.9), adrenal (RPKM 7.5) and 22 other tissues See more
Orthologs
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Genomic context

See NRSN2 in Genome Data Viewer
Location:
20p13
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (346775..359705)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (327755..335506)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 7859/9812 Neighboring gene SRY-box transcription factor 12 Neighboring gene uncharacterized LOC101929937 Neighboring gene Sharpr-MPRA regulatory region 10396 Neighboring gene tribbles pseudokinase 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ23329

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 
is_active_in transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in transport vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001323679.2NP_001310608.1  neurensin-2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK026982, BC001963, BP251173
    UniProtKB/Swiss-Prot
    Q9GZP1
  2. NM_001323680.2NP_001310609.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK026982, BC001963, CD102518, DA479487
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  3. NM_001323681.2NP_001310610.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK026982, BC001963, CD102518
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  4. NM_001323682.2NP_001310611.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK026982, BC001963, BP202782
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Related
    ENSP00000371722.2, ENST00000382285.7
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  5. NM_001323683.2NP_001310612.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL034548, AW292804
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  6. NM_001323684.2NP_001310613.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL034548, AW292804, DA708181
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  7. NM_001323685.2NP_001310614.1  neurensin-2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AK026982, BC001963, DB172225
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  8. NM_024958.3NP_079234.1  neurensin-2 isoform 1

    See identical proteins and their annotated locations for NP_079234.1

    Status: VALIDATED

    Source sequence(s)
    AL136915, BC001963, BE792891, DA708181
    Consensus CDS
    CCDS12996.1
    UniProtKB/Swiss-Prot
    Q9GZP1
    Related
    ENSP00000371728.3, ENST00000382291.7
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin

RNA

  1. NR_136649.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL034548, BC001963, DA708181

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    346775..359705
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529360.1XP_011527662.1  neurensin-2 isoform X1

    See identical proteins and their annotated locations for XP_011527662.1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  2. XM_011529362.3XP_011527664.1  neurensin-2 isoform X1

    See identical proteins and their annotated locations for XP_011527664.1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  3. XM_017028073.1XP_016883562.1  neurensin-2 isoform X1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  4. XM_017028075.1XP_016883564.1  neurensin-2 isoform X1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  5. XM_006723630.4XP_006723693.1  neurensin-2 isoform X1

    See identical proteins and their annotated locations for XP_006723693.1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  6. XM_017028074.2XP_016883563.1  neurensin-2 isoform X1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  7. XM_011529363.2XP_011527665.1  neurensin-2 isoform X1

    See identical proteins and their annotated locations for XP_011527665.1

    UniProtKB/Swiss-Prot
    Q9GZP1
    Conserved Domains (1) summary
    pfam14927
    Location:22155
    Neurensin
  8. XM_017028076.1XP_016883565.1  neurensin-2 isoform X2

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