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rereb arginine-glutamic acid dipeptide (RE) repeats b [ Danio rerio (zebrafish) ]

Gene ID: 799473, updated on 12-Sep-2024

Summary

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Official Symbol
rerebprovided by ZNC
Official Full Name
arginine-glutamic acid dipeptide (RE) repeats bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070212-3
See related
Ensembl:ENSDARG00000075670 AllianceGenome:ZFIN:ZDB-GENE-070212-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable transcription corepressor activity. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human RERE (arginine-glutamic acid dipeptide repeats). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See rereb in Genome Data Viewer
Location:
chromosome: 6
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (40671341..40690078)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (40672961..40693178)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 1 Neighboring gene microRNA 200c Neighboring gene enolase 1b, (alpha) Neighboring gene PPARGC1 and ESRR induced regulator, muscle 1b Neighboring gene RING finger protein 223 Neighboring gene si:ch211-157b11.12 Neighboring gene interactor of HORMAD1 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arginine-glutamic acid dipeptide repeats protein
Names
rerea

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    40671341..40690078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166103.4 → XP_005166160.1  arginine-glutamic acid dipeptide repeats protein isoform X1

    UniProtKB/TrEMBL
    A0A8M2BDH9, E7FCG5
    Related
    ENSDARP00000101018.2, ENSDART00000111639.4
    Conserved Domains (5) summary
    smart00717
    Location:126 → 173
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:127 → 172
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    cd00202
    Location:235 → 270
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam01448
    Location:18 → 68
    ELM2; ELM2 domain
    pfam03154
    Location:294 → 1215
    Atrophin-1; Atrophin-1 family

  2. XM_009302602.3 → XP_009300877.1  arginine-glutamic acid dipeptide repeats protein isoform X2

    UniProtKB/TrEMBL
    A0A8M3ATK3
    Conserved Domains (5) summary
    smart00717
    Location:126 → 173
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:127 → 172
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    cd00202
    Location:235 → 270
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam01448
    Location:18 → 68
    ELM2; ELM2 domain
    pfam03154
    Location:294 → 1200
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
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