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RERGL RERG like [ Homo sapiens (human) ]

Gene ID: 79785, updated on 25-Jan-2022

Summary

Official Symbol
RERGLprovided by HGNC
Official Full Name
RERG likeprovided by HGNC
Primary source
HGNC:HGNC:26213
See related
Ensembl:ENSG00000111404 AllianceGenome:HGNC:26213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable G protein activity and GTP binding activity. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in endometrium (RPKM 13.0), fat (RPKM 12.7) and 18 other tissues See more
Orthologs
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Genomic context

See RERGL in Genome Data Viewer
Location:
12p12.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (18080869..18090193, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (18233803..18243127, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs579 Neighboring gene VISTA enhancer hs980 Neighboring gene microRNA 3974 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Neighboring gene Nedd4 family interacting protein 1 pseudogene 1 Neighboring gene zinc finger with KRAB and SCAN domains 7 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ22655

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ras-related and estrogen-regulated growth inhibitor-like protein
Names
RERG/RAS-like
NP_001273130.1
NP_079006.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052618.1 RefSeqGene

    Range
    5001..14325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001286201.2NP_001273130.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform b

    See identical proteins and their annotated locations for NP_001273130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    BC042888, BX422875, DT220095
    Consensus CDS
    CCDS66332.1
    UniProtKB/Swiss-Prot
    Q9H628
    UniProtKB/TrEMBL
    F5H686
    Related
    ENSP00000437814.1, ENST00000538724.6
    Conserved Domains (1) summary
    cd04146
    Location:5173
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families
  2. NM_024730.4NP_079006.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform a

    See identical proteins and their annotated locations for NP_079006.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    BC042888, DT220095
    Consensus CDS
    CCDS8679.1
    UniProtKB/Swiss-Prot
    Q9H628
    Related
    ENSP00000229002.2, ENST00000229002.6
    Conserved Domains (1) summary
    cd04146
    Location:6174
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

RNA

  1. NR_104413.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA220227, BC042888, BX422875, DT220095

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    18080869..18090193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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