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RERGL RERG like [ Homo sapiens (human) ]

Gene ID: 79785, updated on 9-Jun-2025
Official Symbol
RERGLprovided by HGNC
Official Full Name
RERG likeprovided by HGNC
Primary source
HGNC:HGNC:26213
See related
Ensembl:ENSG00000111404 AllianceGenome:HGNC:26213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable G protein activity and GTP binding activity. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Broad expression in endometrium (RPKM 13.0), fat (RPKM 12.7) and 18 other tissues See more
Orthologs
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See RERGL in Genome Data Viewer
Location:
12p12.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (18080869..18090193, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (17957086..17966409, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (18233803..18243127, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902888 Neighboring gene uncharacterized LOC124902889 Neighboring gene VISTA enhancer hs579 Neighboring gene VISTA enhancer hs980 Neighboring gene microRNA 3974 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18102760-18103303 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:18306612-18307209 Neighboring gene uncharacterized LOC124903122 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18355246-18356201 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:18356202-18357156 Neighboring gene uncharacterized LOC124902890 Neighboring gene phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Markers

Clone Names

  • FLJ22655

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ras-related and estrogen-regulated growth inhibitor-like protein
Names
RERG/RAS-like
NP_001273130.1
NP_079006.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_052618.1 RefSeqGene

    Range
    5001..14325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001286201.2NP_001273130.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform b

    See identical proteins and their annotated locations for NP_001273130.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    BC042888, BX422875, DT220095
    Consensus CDS
    CCDS66332.1
    UniProtKB/TrEMBL
    F5H686
    Related
    ENSP00000437814.1, ENST00000538724.6
    Conserved Domains (1) summary
    cd04146
    Location:5173
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families
  2. NM_024730.4NP_079006.1  ras-related and estrogen-regulated growth inhibitor-like protein isoform a

    See identical proteins and their annotated locations for NP_079006.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    BC042888, DT220095
    Consensus CDS
    CCDS8679.1
    UniProtKB/Swiss-Prot
    Q9H628
    Related
    ENSP00000229002.2, ENST00000229002.6
    Conserved Domains (1) summary
    cd04146
    Location:6174
    RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families

RNA

  1. NR_104413.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AA220227, BC042888, BX422875, DT220095

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    18080869..18090193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    17957086..17966409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)