Format

Send to:

Choose Destination

DIPK2B divergent protein kinase domain 2B [ Homo sapiens (human) ]

Gene ID: 79742, updated on 23-Nov-2021

Summary

Official Symbol
DIPK2Bprovided by HGNC
Official Full Name
divergent protein kinase domain 2Bprovided by HGNC
Primary source
HGNC:HGNC:25866
See related
Ensembl:ENSG00000147113 MIM:300959
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DIA1R; CXorf36; PRO3743; EPQL1862; bA435K1.1; 4930578C19Rik
Expression
Broad expression in placenta (RPKM 14.6), fat (RPKM 13.7) and 19 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See DIPK2B in Genome Data Viewer
Location:
Xp11.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (45148373..45200876, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (45007618..45060121, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373190 Neighboring gene lysine demethylase 6A Neighboring gene uncharacterized LOC105373191 Neighboring gene PLLP pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14103, FLJ55198, DKFZp313K0825

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
divergent protein kinase domain 2B
Names
UPF0672 protein CXorf36
deleted in autism-1 related protein
deleted in autism-related protein 1
hCG1981635

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_027895.1 RefSeqGene

    Range
    5026..43579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_024689.3NP_078965.2  divergent protein kinase domain 2B isoform 2 precursor

    See identical proteins and their annotated locations for NP_078965.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different segment for the 3' coding region and 3' UTR, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus when it is compared to isoform 1.
    Source sequence(s)
    AK024165, BC035375, BP231945
    Consensus CDS
    CCDS14266.1
    UniProtKB/Swiss-Prot
    Q9H7Y0
    Related
    ENSP00000367168.4, ENST00000377934.4
  2. NM_176819.4NP_789789.2  divergent protein kinase domain 2B isoform 1 precursor

    See identical proteins and their annotated locations for NP_789789.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).
    Source sequence(s)
    AC136488, AF289581, AK024165, BP231945, DA378381, DC332862
    Consensus CDS
    CCDS48096.1
    UniProtKB/Swiss-Prot
    Q9H7Y0
    UniProtKB/TrEMBL
    Q8WZ11
    Related
    ENSP00000381086.2, ENST00000398000.7
    Conserved Domains (1) summary
    pfam12260
    Location:211389
    PIP49_C; Protein-kinase domain of FAM69

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    45148373..45200876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006724559.1XP_006724622.1  divergent protein kinase domain 2B isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:164305
    PKc_like; Protein Kinases, catalytic domain
  2. XM_005272670.1XP_005272727.1  divergent protein kinase domain 2B isoform X1

    Conserved Domains (1) summary
    pfam12260
    Location:164331
    PIP49_C; Protein-kinase domain of FAM69
Support Center