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RTL10 retrotransposon Gag like 10 [ Homo sapiens (human) ]

Gene ID: 79680, updated on 5-Aug-2022

Summary

Official Symbol
RTL10provided by HGNC
Official Full Name
retrotransposon Gag like 10provided by HGNC
Primary source
HGNC:HGNC:26112
See related
Ensembl:ENSG00000215012 AllianceGenome:HGNC:26112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BOP; C22orf29
Summary
Involved in mitochondrial outer membrane permeabilization and regulation of mitochondrial membrane potential. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in skin (RPKM 6.6), brain (RPKM 5.5) and 25 other tissues See more
Orthologs
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Genomic context

See RTL10 in Genome Data Viewer
Location:
22q11.21
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (19846146..19854874, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (20223015..20231743, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (19833669..19842397, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs515 Neighboring gene T-box transcription factor 1 Neighboring gene G protein subunit beta 1 like Neighboring gene ribosomal protein L7a pseudogene 70 Neighboring gene uncharacterized LOC124905080 Neighboring gene thioredoxin reductase 2 Neighboring gene ribosomal protein L8 pseudogene 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21125

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein Bop
Names
BH3-only protein
retrotransposon Gag-like protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024627.6NP_078903.3  protein Bop

    See identical proteins and their annotated locations for NP_078903.3

    Status: VALIDATED

    Source sequence(s)
    AC000076, AK026924, BC011679, DA182195, DA757523
    Consensus CDS
    CCDS13769.1
    UniProtKB/Swiss-Prot
    Q7L3V2, Q9H7A0
    Related
    ENSP00000330596.4, ENST00000328554.9
    Conserved Domains (1) summary
    pfam16297
    Location:104178
    DUF4939; Domain of unknown function (DUF4939)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    19846146..19854874 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    20223015..20231743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)