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FAM118B family with sequence similarity 118 member B [ Homo sapiens (human) ]

Gene ID: 79607, updated on 7-Jun-2020

Summary

Official Symbol
FAM118Bprovided by HGNC
Official Full Name
family with sequence similarity 118 member Bprovided by HGNC
Primary source
HGNC:HGNC:26110
See related
Ensembl:ENSG00000197798 MIM:616587
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 26.8), salivary gland (RPKM 21.2) and 25 other tissues See more
Orthologs

Genomic context

See FAM118B in Genome Data Viewer
Location:
11q24.2
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (126211414..126264540)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (126081619..126132879)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369591 Neighboring gene HNF4 motif-containing MPRA enhancer 115 Neighboring gene RNA pseudouridine synthase D4 Neighboring gene RNA, U4 small nuclear 86, pseudogene Neighboring gene RNA, 7SL, cytoplasmic 351, pseudogene Neighboring gene SRP receptor subunit alpha Neighboring gene FAD dependent oxidoreductase domain containing 1 Neighboring gene ribosomal protein L35a pseudogene 26

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21103

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Cajal body organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Cajal body IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_017156.1 RefSeqGene

    Range
    5059..56245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001330446.1NP_001317375.1  protein FAM118B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP001318, BI522660, CB141933
    Consensus CDS
    CCDS81647.1
    UniProtKB/TrEMBL
    J3KP39
    Related
    ENSP00000434952.1, ENST00000528985.5
    Conserved Domains (1) summary
    pfam13289
    Location:158301
    SIR2_2; SIR2-like domain
  2. NM_024556.4NP_078832.1  protein FAM118B isoform 1

    See identical proteins and their annotated locations for NP_078832.1

    Status: VALIDATED

    Source sequence(s)
    BC001340, BF448999, CB141933
    Consensus CDS
    CCDS8470.1
    UniProtKB/Swiss-Prot
    Q9BPY3
    UniProtKB/TrEMBL
    A0A024R3L8
    Related
    ENSP00000433343.1, ENST00000533050.6
    Conserved Domains (1) summary
    pfam13289
    Location:158301
    SIR2_2; SIR2-like domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    126211414..126264540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017018286.1XP_016873775.1  protein FAM118B isoform X4

  2. XM_011542977.3XP_011541279.1  protein FAM118B isoform X1

    See identical proteins and their annotated locations for XP_011541279.1

    UniProtKB/Swiss-Prot
    Q9BPY3
    UniProtKB/TrEMBL
    A0A024R3L8
    Conserved Domains (1) summary
    pfam13289
    Location:158301
    SIR2_2; SIR2-like domain
  3. XM_017018285.2XP_016873774.1  protein FAM118B isoform X2

    UniProtKB/TrEMBL
    J3KP39
    Related
    ENSP00000353321.4, ENST00000360194.8
    Conserved Domains (1) summary
    pfam13289
    Location:158301
    SIR2_2; SIR2-like domain
  4. XM_011542978.3XP_011541280.1  protein FAM118B isoform X3

    See identical proteins and their annotated locations for XP_011541280.1

    Conserved Domains (1) summary
    pfam13289
    Location:38146
    SIR2_2; SIR2-like domain
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