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PRR15L proline rich 15 like [ Homo sapiens (human) ]

Gene ID: 79170, updated on 1-Aug-2020

Summary

Official Symbol
PRR15Lprovided by HGNC
Official Full Name
proline rich 15 likeprovided by HGNC
Primary source
HGNC:HGNC:28149
See related
Ensembl:ENSG00000167183
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATAD4
Expression
Biased expression in duodenum (RPKM 78.9), small intestine (RPKM 58.5) and 11 other tissues See more
Orthologs

Genomic context

See PRR15L in Genome Data Viewer
Location:
17q21.32
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (47951967..47957905, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46029333..46035252, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene SP2 antisense RNA 1 Neighboring gene Sp2 transcription factor Neighboring gene pyridoxamine 5'-phosphate oxidase Neighboring gene CDK5 regulatory subunit associated protein 3 Neighboring gene COPI coat complex subunit zeta 2 Neighboring gene microRNA 10226

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC11242

General protein information

Preferred Names
proline-rich protein 15-like protein
Names
ATPase family, AAA domain containing 4
testicular tissue protein Li 157

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024320.4NP_077296.1  proline-rich protein 15-like protein

    See identical proteins and their annotated locations for NP_077296.1

    Status: VALIDATED

    Source sequence(s)
    AA707319, AA916635, AC018521, BM829856, BM831136
    Consensus CDS
    CCDS11523.1
    UniProtKB/Swiss-Prot
    Q9BU68
    UniProtKB/TrEMBL
    A0A140VJT1
    Related
    ENSP00000300557.2, ENST00000300557.3
    Conserved Domains (1) summary
    pfam15321
    Location:788
    ATAD4; ATPase family AAA domain containing 4

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    47951967..47957905 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005257666.4XP_005257723.1  proline-rich protein 15-like protein isoform X1

    See identical proteins and their annotated locations for XP_005257723.1

    UniProtKB/Swiss-Prot
    Q9BU68
    UniProtKB/TrEMBL
    A0A140VJT1
    Conserved Domains (1) summary
    pfam15321
    Location:788
    ATAD4; ATPase family AAA domain containing 4
  2. XM_005257663.4XP_005257720.1  proline-rich protein 15-like protein isoform X1

    See identical proteins and their annotated locations for XP_005257720.1

    UniProtKB/Swiss-Prot
    Q9BU68
    UniProtKB/TrEMBL
    A0A140VJT1
    Conserved Domains (1) summary
    pfam15321
    Location:788
    ATAD4; ATPase family AAA domain containing 4
  3. XM_005257664.2XP_005257721.1  proline-rich protein 15-like protein isoform X1

    See identical proteins and their annotated locations for XP_005257721.1

    UniProtKB/Swiss-Prot
    Q9BU68
    UniProtKB/TrEMBL
    A0A140VJT1
    Conserved Domains (1) summary
    pfam15321
    Location:788
    ATAD4; ATPase family AAA domain containing 4
  4. XM_005257665.1XP_005257722.1  proline-rich protein 15-like protein isoform X1

    See identical proteins and their annotated locations for XP_005257722.1

    UniProtKB/Swiss-Prot
    Q9BU68
    UniProtKB/TrEMBL
    A0A140VJT1
    Conserved Domains (1) summary
    pfam15321
    Location:788
    ATAD4; ATPase family AAA domain containing 4
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