C7orf26 chromosome 7 open reading frame 26 [Homo sapiens (human)] - Gene

Summary

Official Symbol: C7orf26provided by HGNC
Official Full Name: chromosome 7 open reading frame 26provided by HGNC
Primary source: HGNC:HGNC:21702
See related: Ensembl:ENSG00000146576
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression: Ubiquitous expression in testis (RPKM 9.0), spleen (RPKM 8.0) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 7p22.1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
109.20211119	current	GRCh38.p13 (GCF_000001405.39)	7	NC_000007.14 (6590021..6608726)
105.20201022	previous assembly	GRCh37.p13 (GCF_000001405.25)	7	NC_000007.13 (6629652..6648357)

Chromosome 7 - NC_000007.14 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

A008D23 (e-PCR)
- UniSTS:27450

RH12045 (e-PCR)
- UniSTS:41557

SHGC-55949 (e-PCR)
- UniSTS:41558

D7S2646 (e-PCR)
- UniSTS:34431

STS-Z41394 (e-PCR)
- UniSTS:25243

GDB:4585098 (e-PCR)
- UniSTS:16051

RH48523 (e-PCR)
- UniSTS:80575

Homology

Homologs of the C7orf26 gene: The C7orf26 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog.
Orthologs from Annotation Pipeline: 409 organisms have orthologs with human gene C7orf26
Orthologs

General protein information

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Preferred Names: uncharacterized protein C7orf26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001303039.2 → NP_001289968.1 uncharacterized protein C7orf26 isoform 2

See identical proteins and their annotated locations for NP_001289968.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, and lacks an alternate in-frame segment in the central coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

Source sequence(s)

BC001076, BI599533, BM977018, CA454040

Consensus CDS

CCDS78206.1

UniProtKB/Swiss-Prot

Q96N11

Related

ENSP00000351974.5, ENST00000359073.9

Conserved Domains (1) summary

pfam14964
Location:2 → 284

DUF4507; Domain of unknown function (DUF4507)
NM_024067.4 → NP_076972.2 uncharacterized protein C7orf26 isoform 1

See identical proteins and their annotated locations for NP_076972.2

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Source sequence(s)

AK056149, BI599533, BM977018, CA454040

Consensus CDS

CCDS5353.1

UniProtKB/Swiss-Prot

Q96N11

Related

ENSP00000340220.5, ENST00000344417.10

Conserved Domains (1) summary

pfam14964
Location:2 → 381

DUF4507; Domain of unknown function (DUF4507)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

NC_000007.14 Reference GRCh38.p13 Primary Assembly

Range

6590021..6608726

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005249845.5 → XP_005249902.1 uncharacterized protein C7orf26 isoform X1

Conserved Domains (1) summary

pfam14964
Location:2 → 381

DUF4507; Domain of unknown function (DUF4507)
XM_011515518.3 → XP_011513820.1 uncharacterized protein C7orf26 isoform X3

Conserved Domains (1) summary

pfam14964
Location:2 → 381

DUF4507; Domain of unknown function (DUF4507)
XM_017012614.2 → XP_016868103.1 uncharacterized protein C7orf26 isoform X2
XM_017012615.1 → XP_016868104.1 uncharacterized protein C7orf26 isoform X4