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METRN meteorin, glial cell differentiation regulator [ Homo sapiens (human) ]

Gene ID: 79006, updated on 1-Jun-2020

Summary

Official Symbol
METRNprovided by HGNC
Official Full Name
meteorin, glial cell differentiation regulatorprovided by HGNC
Primary source
HGNC:HGNC:14151
See related
Ensembl:ENSG00000103260 MIM:610998
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C16orf23; c380A1.2
Summary
Meteorin regulates glial cell differentiation and promotes the formation of axonal networks during neurogenesis (Nishino et al., 2004 [PubMed 15085178]).[supplied by OMIM, Mar 2008]
Expression
Broad expression in brain (RPKM 10.2), kidney (RPKM 4.0) and 23 other tissues See more
Orthologs

Genomic context

See METRN in Genome Data Viewer
Location:
16p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (715118..719655)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (765173..769655)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene WD repeat domain 24 Neighboring gene F-box and leucine rich repeat protein 16 Neighboring gene adenine nucleotide translocase lysine methyltransferase Neighboring gene coiled-coil domain containing 78 Neighboring gene hydroxyacylglutathione hydrolase like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC2601

Gene Ontology Provided by GOA

Function Evidence Code Pubs
hormone activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
glial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024042.4NP_076947.1  meteorin precursor

    See identical proteins and their annotated locations for NP_076947.1

    Status: VALIDATED

    Source sequence(s)
    AL360260, BC000662, Z97653, Z98258
    Consensus CDS
    CCDS10422.1
    UniProtKB/Swiss-Prot
    Q9UJH8
    Related
    ENSP00000455068.1, ENST00000568223.7

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    715118..719655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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