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AUNIP aurora kinase A and ninein interacting protein [ Homo sapiens (human) ]

Gene ID: 79000, updated on 11-Jun-2021

Summary

Official Symbol
AUNIPprovided by HGNC
Official Full Name
aurora kinase A and ninein interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:28363
See related
Ensembl:ENSG00000127423
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AIBP; C1orf135
Expression
Broad expression in testis (RPKM 11.8), adrenal (RPKM 7.3) and 24 other tissues See more
Orthologs
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Genomic context

See AUNIP in Genome Data Viewer
Location:
1p36.11
Exon count:
4
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (25831906..25859457, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (26158397..26185948, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene selenoprotein N Neighboring gene uncharacterized LOC646471 Neighboring gene mitochondrial fission regulator 1 like Neighboring gene progestin and adipoQ receptor family member 7 Neighboring gene stathmin 1 Neighboring gene small nuclear ribonucleoprotein polypeptide F pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC2603, FLJ14264

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables damaged DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in site of DNA damage IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
aurora kinase A and ninein-interacting protein
Names
aurora A-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001287490.2NP_001274419.1  aurora kinase A and ninein-interacting protein isoform 1

    See identical proteins and their annotated locations for NP_001274419.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL020996, BF987554, BJ989876, GQ844687
    Consensus CDS
    CCDS72731.1
    UniProtKB/Swiss-Prot
    Q9H7T9
    Related
    ENSP00000443647.1, ENST00000538789.5
    Conserved Domains (1) summary
    pfam15334
    Location:26348
    AIB; Aurora kinase A and ninein interacting protein
  2. NM_024037.3NP_076942.1  aurora kinase A and ninein-interacting protein isoform 2

    See identical proteins and their annotated locations for NP_076942.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AI198661, AL020996, BC000209, BJ989876
    Consensus CDS
    CCDS266.1
    UniProtKB/Swiss-Prot
    Q9H7T9
    Related
    ENSP00000363416.4, ENST00000374298.4
    Conserved Domains (1) summary
    pfam15334
    Location:26350
    AIB; Aurora kinase A and ninein interacting protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    25831906..25859457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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