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H2bc27 H2B clustered histone 27 [ Mus musculus (house mouse) ]

Gene ID: 78303, updated on 5-Jan-2023

Summary

Official Symbol
H2bc27provided by MGI
Official Full Name
H2B clustered histone 27provided by MGI
Primary source
MGI:MGI:1925553
See related
Ensembl:ENSMUSG00000056895 AllianceGenome:MGI:1925553
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2bu2; Hist3h2ba; 1500011O09Rik
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. [provided by RefSeq, Sep 2015]
Orthologs
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Genomic context

See H2bc27 in Genome Data Viewer
Location:
11; 11 B1.3
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58839737..58840198)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58948911..58949372)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene butyrophilin-like 10 Neighboring gene ring finger protein 187 Neighboring gene predicted gene, 51864 Neighboring gene H2B.U histone 1, pseudogene Neighboring gene H2A clustered histone 25 Neighboring gene tripartite motif-containing 17

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
H2B.U histone 2
Names
histone 3, H2ba
histone H2B type 3-A
histone cluster 3, H2ba

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030082.4NP_084358.1  H2B.U histone 2

    See identical proteins and their annotated locations for NP_084358.1

    Status: REVIEWED

    Source sequence(s)
    AL662809
    Consensus CDS
    CCDS24754.1
    UniProtKB/Swiss-Prot
    Q9D2U9
    UniProtKB/TrEMBL
    A0A6P5QIZ6, A0A8C6HSD3
    Related
    ENSMUSP00000076397.4, ENSMUST00000078267.5
    Conserved Domains (1) summary
    cl23830
    Location:12125
    H2B; Histone H2B

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    58839737..58840198
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)