scg2b secretogranin II b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: scg2bprovided by ZNC
Official Full Name: secretogranin II bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061103-160
See related: Ensembl:ENSDARG00000038574 AllianceGenome:ZFIN:ZDB-GENE-061103-160
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: scg2; sgIIb; wu:fj34e01; zgc:153925
Summary: Acts upstream of or within regulation of sprouting angiogenesis. Predicted to be located in extracellular region and secretory granule. Is expressed in brain; central nervous system; and hindbrain. Orthologous to human SCG2 (secretogranin II). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (47582024..47585197)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (47727877..47731033)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Targeted mutation of secretogranin-2 disrupts sexual behavior and reproduction in zebrafish.
Title: Targeted mutation of secretogranin-2 disrupts sexual behavior and reproduction in zebrafish.
SgIIb is expressed in the central nervous system of zebrafish embryos and sgIIb-expressing neurons and central arteries are aligned in the hindbrain.
Title: Secretogranin-II plays a critical role in zebrafish neurovascular modeling.

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within angiogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of sprouting angiogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in secretory granule	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: secretogranin-2b

Names: secretogranin II (chromogranin C), b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.