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Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 [ Mus musculus (house mouse) ]

Gene ID: 75406, updated on 8-Jul-2021

Summary

Official Symbol
Ndufs7provided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase core subunit S7provided by MGI
Primary source
MGI:MGI:1922656
See related
Ensembl:ENSMUSG00000020153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CI-20kD; 1010001M04Rik
Expression
Ubiquitous expression in heart adult (RPKM 322.2), duodenum adult (RPKM 296.5) and 28 other tissues See more
Orthologs
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Genomic context

See Ndufs7 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80084939..80092628)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80249105..80256794)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79712197..79719537)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene PWWP domain containing 3A, DNA repair factor Neighboring gene nuclear encoded tRNA pheylalanine 3 (anticodon GAA) Neighboring gene nuclear encoded tRNA asparagine 7 (anticodon GTT) Neighboring gene guanidinoacetate methyltransferase Neighboring gene DAZ associated protein 1 Neighboring gene microRNA 6911

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables NADH dehydrogenase (ubiquinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables NADH dehydrogenase (ubiquinone) activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to NADH dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
enables quinone binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in electron transport coupled proton transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial electron transport, NADH to ubiquinone ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial respiratory chain complex I assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane HDA PubMed 
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of mitochondrial respiratory chain complex I ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in respirasome IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Names
NADH dehydrogenase (ubiquinone) Fe-S protein 7
NADH-ubiquinone oxidoreductase 20 kDa subunit
complex I-20kD
NP_001351623.1
NP_083548.1
XP_006514333.1
XP_030101204.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364694.1NP_001351623.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC140229
    Conserved Domains (1) summary
    PRK06411
    Location:74192
    PRK06411; NADH dehydrogenase subunit B; Validated
  2. NM_029272.4NP_083548.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform 1 precursor

    See identical proteins and their annotated locations for NP_083548.1

    Status: VALIDATED

    Source sequence(s)
    AC140229
    Consensus CDS
    CCDS24015.1
    UniProtKB/Swiss-Prot
    Q9DC70
    Related
    ENSMUSP00000020361.7, ENSMUST00000020361.7
    Conserved Domains (1) summary
    PRK06411
    Location:74224
    PRK06411; NADH-quinone oxidoreductase subunit NuoB

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    80084939..80092628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514270.2XP_006514333.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X2

    Conserved Domains (1) summary
    PRK06411
    Location:46196
    PRK06411; NADH-quinone oxidoreductase subunit NuoB
  2. XM_030245344.2XP_030101204.1  NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1

    Related
    ENSMUSP00000101003.2, ENSMUST00000105364.8
    Conserved Domains (1) summary
    PRK06411
    Location:74224
    PRK06411; NADH-quinone oxidoreductase subunit NuoB
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