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Sv2c synaptic vesicle glycoprotein 2c [ Mus musculus (house mouse) ]

Gene ID: 75209, updated on 21-Apr-2024

Summary

Official Symbol
Sv2cprovided by MGI
Official Full Name
synaptic vesicle glycoprotein 2cprovided by MGI
Primary source
MGI:MGI:1922459
See related
Ensembl:ENSMUSG00000051111 AllianceGenome:MGI:1922459
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930527L09Rik
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within chemical synaptic transmission. Located in synaptic vesicle. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SV2C (synaptic vesicle glycoprotein 2C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 6.9), frontal lobe adult (RPKM 2.3) and 6 other tissues See more
Orthologs
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Genomic context

Location:
13 D1; 13 50.47 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (96091102..96270837, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (95959443..96132577, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene IQ motif containing GTPase activating protein 2 Neighboring gene predicted gene, 32702 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:96662105-96662214 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:96662521-96662711 Neighboring gene predicted gene, 24032 Neighboring gene STARR-positive B cell enhancer mm9_chr13:96730579-96730880 Neighboring gene STARR-seq mESC enhancer starr_35333 Neighboring gene predicted gene, 57605 Neighboring gene STARR-seq mESC enhancer starr_35337 Neighboring gene basic transcription factor 3 like 4B Neighboring gene predicted gene 17190 Neighboring gene predicted gene, 23955 Neighboring gene predicted gene 29543 Neighboring gene STARR-seq mESC enhancer starr_35340 Neighboring gene STARR-seq mESC enhancer starr_35341 Neighboring gene STARR-seq mESC enhancer starr_35342 Neighboring gene STARR-seq mESC enhancer starr_35344 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:97157941-97158317 Neighboring gene SNF8, ESCRT-II complex subunit, homolog pseudogene Neighboring gene ankyrin repeat and death domain containing 1B Neighboring gene POC5 centriolar protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in dopaminergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in dopaminergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
synaptic vesicle glycoprotein 2C
Names
synaptic vesicle protein 2C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029210.1NP_083486.1  synaptic vesicle glycoprotein 2C

    See identical proteins and their annotated locations for NP_083486.1

    Status: VALIDATED

    Source sequence(s)
    AC129327, AC153134
    Consensus CDS
    CCDS49333.1
    UniProtKB/Swiss-Prot
    Q69ZS6
    UniProtKB/TrEMBL
    A2RSH4
    Related
    ENSMUSP00000124473.2, ENSMUST00000161263.8
    Conserved Domains (1) summary
    TIGR01299
    Location:1727
    synapt_SV2; synaptic vesicle protein SV2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    96091102..96270837 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158202.1XP_036014095.1  synaptic vesicle glycoprotein 2C isoform X1

    UniProtKB/Swiss-Prot
    Q69ZS6
    UniProtKB/TrEMBL
    A2RSH4
    Conserved Domains (1) summary
    TIGR01299
    Location:1727
    synapt_SV2; synaptic vesicle protein SV2
  2. XM_030247440.2XP_030103300.1  synaptic vesicle glycoprotein 2C isoform X2

    Conserved Domains (1) summary
    TIGR01299
    Location:22307
    synapt_SV2; synaptic vesicle protein SV2