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Atp6v1e2 ATPase, H+ transporting, lysosomal V1 subunit E2 [ Mus musculus (house mouse) ]

Gene ID: 74915, updated on 5-Mar-2024


Official Symbol
Atp6v1e2provided by MGI
Official Full Name
ATPase, H+ transporting, lysosomal V1 subunit E2provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000053375 AllianceGenome:MGI:1922165
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E1; Atp6e1; 4930500C14Rik
Enables proton-transporting ATPase activity, rotational mechanism. Acts upstream of or within proton transmembrane transport. Located in acrosomal vesicle. Orthologous to human ATP6V1E2 (ATPase H+ transporting V1 subunit E2). [provided by Alliance of Genome Resources, Apr 2022]
Restricted expression toward testis adult (RPKM 67.0) See more
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Genomic context

17 E4; 17 56.9 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (87251537..87255315, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (86944109..86947887, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_43494 Neighboring gene endothelial PAS domain protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:87201221-87201489 Neighboring gene STARR-seq mESC enhancer starr_43496 Neighboring gene STARR-positive B cell enhancer ABC_E11652 Neighboring gene transmembrane protein 247 Neighboring gene STARR-positive B cell enhancer ABC_E10976 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:87357353-87357462 Neighboring gene STARR-positive B cell enhancer ABC_E1948 Neighboring gene predicted gene, 57642 Neighboring gene STARR-positive B cell enhancer ABC_E1512 Neighboring gene predicted gene, 50012 Neighboring gene ras homolog family member Q

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
V-type proton ATPase subunit E 2
ATPase, H+ transporting, V1 subunit E-like 2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E-like 2
V-ATPase subunit E 2
lysosomal 31kDa
vacuolar proton pump subunit E 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029121.3NP_083397.3  V-type proton ATPase subunit E 2

    See identical proteins and their annotated locations for NP_083397.3

    Status: VALIDATED

    Source sequence(s)
    AC154492, AK015654
    Consensus CDS
    Q6P8U8, Q810S5, Q9D593
    ENSMUSP00000065285.8, ENSMUST00000065758.8
    Conserved Domains (1) summary
    vATP-synt_E; ATP synthase (E/31 kDa) subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000083.7 Reference GRCm39 C57BL/6J

    87251537..87255315 complement
    GenBank, FASTA, Sequence Viewer (Graphics)