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Mettl23 methyltransferase like 23 [ Mus musculus (house mouse) ]

Gene ID: 74319, updated on 31-Jan-2019

Summary

Official Symbol
Mettl23provided by MGI
Official Full Name
methyltransferase like 23provided by MGI
Primary source
MGI:MGI:1921569
See related
Ensembl:ENSMUSG00000090266
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110005A03Rik; 1500035B17Rik; 4933424L15Rik
Expression
Ubiquitous expression in thymus adult (RPKM 16.8), mammary gland adult (RPKM 12.1) and 28 other tissues See more
Orthologs

Genomic context

See Mettl23 in Genome Data Viewer
Location:
11; 11 E2
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (116843515..116849740)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (116704829..116711054)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene matrix-remodelling associated 7 Neighboring gene jumonji domain containing 6 Neighboring gene serine/arginine-rich splicing factor 2 Neighboring gene major facilitator superfamily domain containing 11 Neighboring gene mannoside acetylglucosaminyltransferase 5, isoenzyme B Neighboring gene predicted gene, 33829

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
heat shock protein binding ISO
Inferred from Sequence Orthology
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cognition ISO
Inferred from Sequence Orthology
more info
 
methylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
methyltransferase-like protein 23

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028865.3NP_083141.3  methyltransferase-like protein 23

    See identical proteins and their annotated locations for NP_083141.3

    Status: VALIDATED

    Source sequence(s)
    AK003450, AW490033, BY122329
    Consensus CDS
    CCDS25679.2
    UniProtKB/Swiss-Prot
    A2AA28
    Related
    ENSMUSP00000101978.3, ENSMUST00000106370.9
    Conserved Domains (1) summary
    cl17173
    Location:63189
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    116843515..116849740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534360.2XP_006534423.1  methyltransferase-like protein 23 isoform X1

    Conserved Domains (1) summary
    cl17173
    Location:3126
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
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