IGF1 insulin like growth factor 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: IGF1provided by VGNC
Official Full Name: insulin like growth factor 1provided by VGNC
Primary source: VGNC:VGNC:5427
Locus tag: CK820_G0016081
See related: Ensembl:ENSPTRG00000024078
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	10	NC_072408.2 (109223036..109307191, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	12	NC_072410.1 (107842807..107926890, complement)

Chromosome 10 - NC_072408.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

RH77802 (e-PCR)
- UniSTS:17665

D12S1962 (e-PCR)
- UniSTS:18699

IGF1 (e-PCR), detects polymorphism
- UniSTS:49688

G10727 (e-PCR)
- UniSTS:31781

WI-21639 (e-PCR)
- UniSTS:7237

D12S1074 (e-PCR)
- UniSTS:42570

NoName (e-PCR)
- UniSTS:482382

A009K41 (e-PCR)
- UniSTS:40791

WI-18971 (e-PCR)
- UniSTS:71779

Igf1 (e-PCR), detects polymorphism
- UniSTS:143467

IGF1_1346 (e-PCR)
- UniSTS:277356

GDB:181478 (e-PCR)
- UniSTS:155246

RH18058 (e-PCR)
- UniSTS:3990

GDB:384821 (e-PCR)
- UniSTS:157100

Igf1 (e-PCR), detects polymorphism
- UniSTS:516546

G32627 (e-PCR)
- UniSTS:117210

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables growth factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin-like growth factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in insulin-like growth factor receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: insulin-like growth factor I

Names: somatomedin C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

109223036..109307191 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001156521.8 → XP_001156521.1 insulin-like growth factor I isoform X7

See identical proteins and their annotated locations for XP_001156521.1

UniProtKB/TrEMBL

A0A2J8N030, A0A663DA94, H2R3T0, K7B673

Related

ENSPTRP00000046022.6

Conserved Domains (1) summary

cd04368
Location:49 → 116

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_001156345.8 → XP_001156345.1 insulin-like growth factor I isoform X6

See identical proteins and their annotated locations for XP_001156345.1

UniProtKB/TrEMBL

A0A2I3T5Y4, A0A2J8N025, A0A2J8N032, A0A663DHR1

Related

ENSPTRP00000084654.1

Conserved Domains (1) summary

cd04368
Location:49 → 116

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_001156403.8 → XP_001156403.1 insulin-like growth factor I isoform X9

See identical proteins and their annotated locations for XP_001156403.1

UniProtKB/TrEMBL

A0A2I3S9J3, A0A2J8N032, A0A2J8N038, A0A663DFM2

Related

ENSPTRP00000073496.1

Conserved Domains (1) summary

cd04368
Location:33 → 100

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_024348024.3 → XP_024203792.1 insulin-like growth factor I isoform X5

Conserved Domains (1) summary

cd04368
Location:66 → 133

IlGF; IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On ...
XM_024348023.3 → XP_024203791.1 insulin-like growth factor I isoform X4

Conserved Domains (1) summary

cd04368
Location:66 → 133

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_063787062.1 → XP_063643132.1 insulin-like growth factor I isoform X8

UniProtKB/TrEMBL

A0A2J8N032
XM_016924056.4 → XP_016779545.2 insulin-like growth factor I isoform X1

Conserved Domains (1) summary

cd04368
Location:66 → 133

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_009426113.5 → XP_009424388.1 insulin-like growth factor I isoform X2

See identical proteins and their annotated locations for XP_009424388.1

UniProtKB/TrEMBL

A0A2I3RUB7, A0A2J8N031, A0A663DHC7

Related

ENSPTRP00000067917.1

Conserved Domains (1) summary

cd04368
Location:49 → 116

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...
XM_009426114.5 → XP_009424389.1 insulin-like growth factor I isoform X3

Conserved Domains (1) summary

cd04368
Location:33 → 100

IlGF; insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On a ...