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Fam83e family with sequence similarity 83, member E [ Mus musculus (house mouse) ]

Gene ID: 73813, updated on 5-Mar-2024

Summary

Official Symbol
Fam83eprovided by MGI
Official Full Name
family with sequence similarity 83, member Eprovided by MGI
Primary source
MGI:MGI:1921063
See related
Ensembl:ENSMUSG00000054161 AllianceGenome:MGI:1921063
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930403C10Rik
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Orthologous to human FAM83E (family with sequence similarity 83 member E). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 185.7), stomach adult (RPKM 49.2) and 4 other tissues See more
Orthologs
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Genomic context

See Fam83e in Genome Data Viewer
Location:
7 B3; 7 29.46 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (45370595..45379179)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45721171..45729755)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene D site albumin promoter binding protein Neighboring gene STARR-positive B cell enhancer ABC_E6545 Neighboring gene sphingosine kinase 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:52973256-52973443 Neighboring gene ribosomal protein L18 Neighboring gene sperm acrosome associated 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:52988906-52989102 Neighboring gene sulfotransferase family, cytosolic, 2B, member 1 Neighboring gene predicted gene, 31597 Neighboring gene STARR-seq mESC enhancer starr_18855 Neighboring gene predicted gene, 39009

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033170.4NP_001028342.2  protein FAM83E

    See identical proteins and their annotated locations for NP_001028342.2

    Status: VALIDATED

    Source sequence(s)
    AC167242
    Consensus CDS
    CCDS39959.2
    UniProtKB/Swiss-Prot
    B9EIA0, Q3UN25, Q80XS7
    Related
    ENSMUSP00000114397.3, ENSMUST00000129507.5
    Conserved Domains (2) summary
    pfam07894
    Location:21292
    DUF1669; Protein of unknown function (DUF1669)
    pfam13091
    Location:151284
    PLDc_2; PLD-like domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    45370595..45379179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541224.3XP_006541287.1  protein FAM83E isoform X1

    Conserved Domains (1) summary
    cl15239
    Location:19229
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

RNA

  1. XR_003946572.1 RNA Sequence