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Tex19.1 testis expressed gene 19.1 [ Mus musculus (house mouse) ]

Gene ID: 73679, updated on 8-Feb-2024

Summary

Official Symbol
Tex19.1provided by MGI
Official Full Name
testis expressed gene 19.1provided by MGI
Primary source
MGI:MGI:1920929
See related
Ensembl:ENSMUSG00000039329 AllianceGenome:MGI:1920929
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tex19; Tex19a; mTex19.1; 2410081M02Rik
Summary
Enables piRNA binding activity. Involved in male gamete generation; negative regulation of transposition; and reciprocal meiotic recombination. Acts upstream of or within several processes, including homologous chromosome pairing at meiosis; posttranscriptional regulation of gene expression; and reproductive structure development. Located in cytoplasm and nucleus. Is expressed in several structures, including blastocyst; brain; early embryo; gonad; and tooth. Orthologous to human TEX19 (testis expressed 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward placenta adult (RPKM 31.5) See more
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Genomic context

See Tex19.1 in Genome Data Viewer
Location:
11 E2; 11 85.0 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (121036969..121039140)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (121146143..121148314)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11793 Neighboring gene testis expressed gene 19.2 Neighboring gene STARR-seq mESC enhancer starr_31377 Neighboring gene urotensin 2 receptor Neighboring gene bromodomain containing 4 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (10)  1 citation
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables piRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell proliferation involved in embryonic placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within homologous chromosome pairing at meiosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male gonad development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within male gonad development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in male meiotic nuclear division IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in placenta development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within post-transcriptional regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of retrotransposition IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within retrotransposon silencing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrotransposon silencing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrotransposon silencing ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within sexual reproduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spongiotrophoblast cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
testis-expressed protein 19.1
Names
testis expressed gene 19
testis-expressed protein 19A
testis-expressed sequence 19A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028602.3NP_082878.2  testis-expressed protein 19.1

    See identical proteins and their annotated locations for NP_082878.2

    Status: VALIDATED

    Source sequence(s)
    AL662887
    Consensus CDS
    CCDS25768.1
    UniProtKB/Swiss-Prot
    Q7TPF0, Q99MV2
    Related
    ENSMUSP00000048592.9, ENSMUST00000039088.9
    Conserved Domains (1) summary
    pfam15553
    Location:1164
    TEX19; Testis-expressed protein 19

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    121036969..121039140
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)