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Pgm1 phosphoglucomutase 1 [ Mus musculus (house mouse) ]

Gene ID: 72157, updated on 10-Oct-2019

Summary

Official Symbol
Pgm1provided by MGI
Official Full Name
phosphoglucomutase 1provided by MGI
Primary source
MGI:MGI:97565
See related
Ensembl:ENSMUSG00000025791
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pgm2; Pgm-2; Pgm1a; AA407108; AI098105; 2610020G18Rik
Annotation information
Note: The name of this locus, Pgm1, was recently updated by Mouse Genomic Informatics to be consistent with mammalian orthologs identified as Pgm1. Note that this gene is frequently referred to as Pgm2 in the literature. [02 Oct 2019]
Expression
Ubiquitous expression in liver E18 (RPKM 86.8), mammary gland adult (RPKM 70.6) and 27 other tissues See more
Orthologs

Genomic context

See Pgm1 in Genome Data Viewer
Location:
4 C6; 4 45.71 cM
Exon count:
11
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (99929451..99987294)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (99602056..99659899)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene integrin beta 3 binding protein (beta3-endonexin) Neighboring gene EF-hand calcium binding domain 7 Neighboring gene U4 spliceosomal RNA Neighboring gene cDNA sequence BC062258 Neighboring gene predicted gene, 35701 Neighboring gene predicted gene 12701 Neighboring gene receptor tyrosine kinase-like orphan receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
intramolecular transferase activity, phosphotransferases IEA
Inferred from Electronic Annotation
more info
 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphoglucomutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphoglucomutase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphoglucomutase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
galactose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucose metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glucose metabolic process ISO
Inferred from Sequence Orthology
more info
 
glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Z disc ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phosphoglucomutase-1
Names
glucose phosphomutase 1
phosphoglucomutase 2
NP_082408.3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028132.3NP_082408.3  phosphoglucomutase-1

    See identical proteins and their annotated locations for NP_082408.3

    Status: VALIDATED

    Source sequence(s)
    AK147982, AK152923
    Consensus CDS
    CCDS18388.1
    UniProtKB/Swiss-Prot
    Q9D0F9
    UniProtKB/TrEMBL
    Q3U6X6
    Related
    ENSMUSP00000061227.9, ENSMUST00000058351.15
    Conserved Domains (2) summary
    cd03085
    Location:5562
    PGM1; Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, ...
    PLN02307
    Location:1562
    PLN02307; phosphoglucomutase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p6 C57BL/6J

    Range
    99929451..99987294
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p6 PATCHES

Genomic

  1. NW_019168509.1 Reference GRCm38.p6 PATCHES

    Range
    272865..330708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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